Category: Extracellular Vesicles

Your search for Extracellular Vesicles returned 15 articles and 223 publications

Articles

graphic on storage conditions of extracellular vesicles (EVs)
Applications

Use of Fluorescence Nanoparticle Tracking Analysis as a tool for quality assessment of EVs

Correct and standardized storage conditions of extracellular vesicles (EVs) are essential prerequisites for the stability of clinical samples and the production of consistent EV batches for therapeutic use.
The loss of EV concentration due to improper storage conditions is associated with a reduced activity and physical integrity.
Check out our new app note on the importance of EV storage conditions and how fluorescence nanoparticle tracking analysis can be used as a quality assessment tool.

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Publications

Biodegradable Mg alloy modified with bioactive exosomes for cardiovascular stent application

Hou, Ya-chen; Li, Jing-an; Cao, Chang; Su, Chang; Qin, Zhen; Zhang, Ge; Guo, Jia-cheng; Tang, Jun-nan; Zhang, Jin-ying; Guan, Shao-kang

Journal of Magnesium and Alloys

2023

ApplicationsCardiovascular DiseasesConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

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Bioprinted constructs that simulate nerve–bone crosstalk to improve microenvironment for bone repair

Wang, Tianchang; Li, Wentao; Zhang, Yuxin; Xu, Xiang; Qiang, Lei; Miao, Weiqiang; Yue, Xiaokun; Jiao, Xin; Zhou, Xianhao; Ma, Zhenjiang; Li, Shuai; Ding, Muliang; Zhu, Junfeng; Yang, Chi; Wang, Hui; Li, Tao; Sun, Xin; Wang, Jinwu

Bioactive Materials

2023

ApplicationsExtracellular VesiclesMicrovesiclesSize MeasurementVesicles

BioprintingexosomesMicroenvironmentNerve–bone crosstalkSchwann cells

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Characterization of cannabis strain‑plant‑derived extracellular vesicles as potential biomarkers

Ipinmoroti, Ayodeji O.; Turner, Ja'kayla; Bellenger, Elizabeth J.; Crenshaw, Brennetta J.; Xu, Junhuan; Reeves, Caitlin; Ajayi, Olufemi; Li, Ting; Matthews, Qiana

Protoplasma

2023

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

CannabidiolCannabisCultivarFiberPlant-derived extracellular vesicles

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Cord Blood Plasma and Placental Mesenchymal Stem Cells-Derived Exosomes Increase Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem Cells While Maintaining Their Stemness

Teleb, Rasha S.; Abdul-Hafez, Amal; Othman, Amira; Ahmed, Ahmed El-Abd; Elsaid, Abdelrahman A.; Arif, Hattan; Zarea, Ahmed A.; Abdulmageed, Mohammed; Mohamed, Hend; Ibrahim, Sherif Abdelfattah; Thiruvenkataramani, Ranga P.; Mohamed, Tarek; Kanada, Masamitsu; Madhukar, Burra V.; Arellano, Myrna Gonzalez; Sayed, Mohammed M.; Qubaisy, Heba M.; Omar, Said A.

Cells

2023

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

exosomesextracellular vesicles (EVs)hematopoietic stem cellsmesenchymal stem cellsplacentaumbilical cordumbilical cord blood transplantation

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Equine mesenchymal stem cell derived extracellular vesicle immunopathology biomarker discovery

Reynolds, David E.; Vallapureddy, Phoebe; Morales, Renee‐Tyler T.; Oh, Daniel; Pan, Menghan; Chintapula, Uday; Linardi, Renata L.; Gaesser, Angela M.; Ortved, Kyla; Ko, Jina

Journal of Extracellular Biology

2023

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

biomarker discoveryequineextracellular vesicleimmunomodulationmesenchymal stem celltherapeutic

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Improved Wound Healing and Skin Regeneration Ability of 3,2′-Dihydroxyflavone-Treated Mesenchymal Stem Cell-Derived Extracellular Vesicles

Kim, Sehee; Shin, Yeokyung; Choi, Yujin; Lim, Kyung-Min; Jeong, Yeojin; Dayem, Ahmed Abdal; Lee, Yoonjoo; An, Jongyub; Song, Kwonwoo; Jang, Soo Bin; Cho, Ssang-Goo

IJMS (International Journal of Molecular Sciences) 24

2023

ApplicationsExosomesExtracellular VesiclesSize MeasurementVesicles

anti-inflammationEVsflavonoidMEK/ERK signalMSCswound healing

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Independent human mesenchymal stromal cellderived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model

Madel, Rabea J.; Börger, Verena; Dittrich, Robin; Bremer, Michel; Tertel, Tobias; Phuong, Nhi Ngo Thi; Baba, Hideo A.; Kordelas, Lambros; Staubach, Simon; Stein, Frank; Haberkant, Per; Hackl, Matthias; Grillari, Regina; Grillari, Johannes; Buer, Jan; Horn, Peter A.; Westendorf, Astrid M.; Brandau, Sven; Kirschning, Carsten J.; Giebel, Bernd

Cytotherapy

2023

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

exosomesextracellular vesiclesgraft-versus-host-diseaseheterogeneitymesenchymal stem cellsmesenchymal stromal cells

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Phosphatidylserine-positive extracellular vesicles boost effector CD8+ T cell responses during viral infection

Rausch, Lisa; Flaskamp, Lavinia; Ashokkumar, Ashretha; Trefzer, Anne; Ried, Christine; Buchholz, Veit R.; Obst, Reinhard; Straub, Tobias; Brocker, Thomas; Kranich, Jan

Proceedings of the National Academy of Sciences

2023

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD8 T cellsexosomesextracellular vesiclesLCMVPhosphatidylserine

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Plasma-derived extracellular vesicles released after endurance exercise exert cardioprotective activity through the activation of antioxidant pathways

Lisi, Veronica; Senesi, Giorgia; Bertola, Nadia; Pecoraro, Matteo; Bolis, Sara; Gualerzi, Alice; Picciolini, Silvia; Raimondi, Andrea; Fantini, Cristina; Moretti, Elisa; Parisi, Attilio; Sgrò, Paolo; Di Luigi, Luigi; Geiger, Roger; Ravera, Silvia; Vassalli, Giuseppe; Caporossi, Daniela; Balbi, Carolina

Redox Biology

2023

ApplicationsCardiovascular DiseasesConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesVesicles

Antioxidant activitycardioprotectionCatalytic activityextracellular vesiclesPhysical exerciseRedox capacity

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Plasma‑derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patients

Tengler, Luisa; Schütz, Julia; Tiedtke, Moritz; Jablonska, Jadwiga; Theodoraki, Marie-Nicole; Nitschke, Katja; Weiß, Christel; Seiz, Elena; Affolter, Annette; Jungbauer, Frederic; Lammert, Anne; Rotter, Nicole; Ludwig, Sonja

Molecular Medicine

2023

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesVesicles

Angiogenesisendothelial cellsexosomesHead and neck cancerPlasmaSmall extracellular vesicles

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Quantitative imaging of vesicle-protein interactions reveals close cooperation among proteins

Cha, Minkwon; Jeong, Sang Hyeok; Jung, Jaehun; Baeg, Yoonjin; Park, Sung-Soo; Bae, Seoyoon; Lim, Chan Seok; Park, Jun Hyuk; Lee, Jie-Oh; Gho, Yong Song; Oh, Seung Wook; Shon, Min Ju

J. Extracell. Vesicles (Journal of Extracellular Vesicles) Volume 12, Issue 5

2023

ApplicationsExtracellular VesiclesSize MeasurementVesicles

CD9cell-derived vesiclesICAM-1integrinvesicle-protein interactions

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Exosomal miR-17-3p Alleviates Programmed Necrosis in Cardiac Ischemia/Reperfusion Injury by Regulating TIMP3 Expression

Zhuyuan Liu, Didi Zhu, Fuchao Yu, Mingming Yang, Dan Huang, Zhenjun Ji, Wenbin Lu, and Genshan Ma

Oxidative Medicine and Cellular Longevity: Oxidative Stress and Programmed Cell Death in Cardiovascular Diseases

2022

ApplicationsCardiovascular DiseasesConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

miRNAmiaMyocardial ischemia/reperfusion injuryReperfusio

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Fetal Membranes Contribute to Drug Transport across the Feto-Maternal Interface Utilizing the Breast Cancer Resistance Protein (BCRP)

Ananthkumar Kammala, Meagan Benson, Esha Ganguly, Enkhtuya Radnaa, Talar Kechichian, Lauren Richardson and Ramkumar Menon

life: New Insights into the Placental and Placental Membrane Pathophysiology of Preterm Birth

2022

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

breast cancer resistance proteindrug transportationpregnancy

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Neutral Sphingomyelinase 2 Mediates Oxidative Stress Effects on Astrocyte Senescence and Synaptic Plasticity Transcripts

Zhu, Zhihui; Quadri, Zainuddin; Crivelli, Simone M.; Elsherbini, Ahmed; Zhang, Liping; Tripathi, Priyanka; Qin, Haiyan; Roush, Emily; Spassieva, Stefka D.; Nikolova-Karakashian, Mariana; McClintock, Timothy S.; Bieberich, Erhard

Molecular neurobiology

2022

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesVesicles

ceramideextracellular vesiclesGrin2boxidative stress

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Synergy of Human Platelet-Derived Extracellular Vesicles with Secretome Proteins Promotes Regenerative Functions

Fausto Gueths Gomes, André Cronemberger Andrade, Martin Wolf, Sarah Hochmann, Linda Krisch, Nicole Maeding, Christof Regl, Rodolphe Poupardin, Patricia Ebner-Peking, Christian G. Huber, Nicole Meisner-Kober, Katharina Schallmoser and Dirk Strunk

Biomedicines

2022

Extracellular VesiclesSize MeasurementVesiclesZeta Potential

EV coronahuman platelet lysateproteomics

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Formation of a protein corona on the surface of extracellular vesicles in blood plasma

Eszter Á. Tóth, Lilla Turiák, Tamás Visnovitz, Csaba Cserép, Anett Mázló, Barbara W. Sódar, András I. Försönits, Gábor Petövári, Anna Sebestyén, Zsolt Komlósi, László Drahos, Ágnes Kittel, György Nagy, Attila Bácsi, Ádám Dénes, Yong Song Gho, Katalin É. Szabó-Taylor, Edit I. Buzás

Journal of Extracellular Vesicles

2021

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

EV isolationEV purificationEV size distributionEVs in blood plasmaEVs in rheumatoid arthritisexternal plasma protein cargomedium sized EVsmEVsNTAplasma protein contaminationplasma protein-coated EVsprotein coronaTHP1 derived EVs

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P2RX7 inhibition reduces breast cancer induced osteolytic lesions – implications for bone metastasis

Karan M. Shah, Luke Tattersall, Aleana Hussain, Sarah C. Macfarlane, Alexander Williamson, Adelina E. Acosta-Martin, Janine T. Erler, Penelope D. Ottewell, Alison Gartland

bioRxiv

2021

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesMetastasisSize MeasurementVesicles

intra-tumoral hypoxiaP2RX7

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Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection

Carina Conzelmann, Rüdiger Groß, Min Zou, Franziska Krüger, André Görgens, Manuela O Gustafsson, Samir El Andaloussi, Jan Münch & Janis A. Müller

Journal of Extracellular Vesicles

2020

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesViruses

Corona virusEV isolationEV purificationsaEVssalivary EVsSARS-CoV-2Zika virus

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Zeta Potential of Extracellular Vesicles: Toward Understanding the Attributes that Determine Colloidal Stability

Getnet Midekessa, Kasun Godakumara, James Ord, Janeli Viil, Freddy Lättekivi, Keerthie Dissanayake, Sergei Kopanchuk, Ago Rinken, Aneta Andronowska, Sourav Bhattacharjee, Toonika Rinken, and Alireza Fazeli

ACS Omega

2020

Extracellular VesiclesVesiclesZeta Potential

Buffer Influence on Zeta Potentialcolloidal stabilityJAr cell derived EVspH influence on zeta potentialsurface chargezeta potential

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Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a

Jung-Hyun Lee, Jochen Dindorf, Martin Eberhardt, Xin Lai, Christian Ostalecki, Nina Koliha, Stefani Gross,Katja Blume, Heiko Bruns, Stefan Wild, Gerold Schuler, Julio Vera, Andreas S Baur

Life Science Alliance

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

extracellular vesiclesmelanomamelanoma treatmentpEVsplasma-derived EVstumor development

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Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material

André Görgens, Michel Bremer, Rita Ferrer-Tur, Florian Murke, Tobias Tertel, Peter A. Horn, Sebastian Thalmann, Joshua A. Welsh, Christine Probst, Coralié Guerin, Chantal M. Boulanger, Jennifer C. Jones, Helmut Hanenberg, Uta Erdbrügger, Joanne Lannigan, Franz L. Ricklefs, Samir El-Andaloussi and Bernd Giebel

Journal of Extracellular Vesicles

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesTechnical NanoparticlesVesicles

Antibody LabellingCD63ev characterizationflow cytometrysEVssingle EV detectionsmall EV characterizationsmall EV identificationsmall EVssubpopulations

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Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism

A B Thrush, G Antoun, M Nikpay, D A Patten, C DeVlugt, J-F Mauger, B L Beauchamp, P Lau, R Reshke, É Doucet, P Imbeault, R Boushel, D Gibbings, J Hager, A Valsesia, R S Slack, O Y Al-Dirbashi, R Dent, R McPherson & M-E Harper.

International Journal of Obesity

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Diet resistanceexosomesfasting conditionshigh fat mealHSP72muscle metabolismobese diet-resistanceobesityoxidative stressplasma proteomicsROS

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Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

Michelle L Pleet, James Erickson, Catherine DeMarino, Robert A Barclay, Maria Cowen, Benjamin Lepene, Janie Liang, Jens H Kuhn, Laura Prugar, Spencer W Stonier, John M Dye, Weidong Zhou, Lance A Liotta, M Javad Aman, Fatah Kashanchi

The Journal of Infectuos Diseases

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesViruses

Apoptosiscell cycleebola treatmentEbola virusEBOVEBOV pathogenesiEBOV treatmentEV biogenesisEVsextracellular vesiclesmonocyte apoptosispoptosis; cell cycleT cell apoptosisVP40

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TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons

Amrita Datta Chaudhuri, Raha M. Dastgheyb, Seung-Wan Yoo, Amanda Trout, C. Conover Talbot Jr, Haiping Hao, Kenneth W. Witwer & Norman J. Haughey.

Cell Death & Disease

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

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An In Vitro Potency Assay for Monitoring the Immunomodulatory Potential of Stromal Cell-Derived Extracellular Vesicles

Karin Pachler, Nina Ketterl, Alexandre Desgeorges, Zsuzsanna A. Dunai, Sandra Laner-Plamberger, Doris Streif, Dirk Strunk, Eva Rohde and Mario Gimona

International Journal of Molecular Sciences

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

exosomesextracellular vesiclesimmune modulationmesenchymalT-cell proliferation

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Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy

Huishan Guo, Maneka Chitiprolu, Luc Roncevic, Charlotte Javalet, Fiona J. Hemming, My Tran Trung, Lingrui Meng, Elyse Latreille, Christiano Tanese de Souza, Danielle McCulloch, R. Mitchell Baldwin, Rebecca Auer, Jocelyn Côté, Ryan Charles Russell, Rémy Sadoul, Derrick Gibbings

Developmental Cell

2017

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

AcidificationAtg5Autophagycancerendosomeexosomesextracellular vesiclesLC3multivesicular bodytumorV1V0-ATPase

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Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

Kolhe R, Hunter M, Liu S, Jadeja RN, Pundkar C, Mondal AK, Mendhe B, Drewry M, Rojiani MV, Liu Y, Isales CM, Guldberg RE, Hamrick MW, Fulzele S

Scientific Reports - Nature

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

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Larger size extracellular vesicle as early biomarker in patients with metastatic pancreatic cancer

Dong Uk Kim, Francis A San Lucas, Matthew Cagley, Bret Stephens, Feven C Mulu, Jonathan Castillo, Vincent Bernard, Gauri R. Varadhachary, Matthew H. G. Katz, Hector A Alvarez, Anirban Maitra;

Journal of Clinical Oncology

2017

ApplicationsCancerConcentration MeasurementExtracellular VesiclesPancreatic CancerSize MeasurementVesicles

Bioactive MoleculesBiomarkerLiquid biopsymetastatispancreatic cancerPDACpredictorstumor progression

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Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer’s Disease Pathology and Improves Cognition in the 5XFAD Mouse

Michael B Dinkins, John Enasko, Caterina Hernandez, Guanghu Wang, Jina Kong, Inas Helwa, Yutao Liu, Alvin V Terry Jr, Erhard Bieberich

The Journal of neuroscience: the official Journal of the Society of Neuroscience

2017

ApplicationsExtracellular VesiclesSize MeasurementVesicles

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