Tag: extracellular vesicles

Petra J. Pederson, Huiyun Liang, Daria Filonov, Susan L. Mooberry

Cancers

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

eribulinexosomesextracellular vesiclesmicrotubule targeting agentsmicrovesicles

Albanese M, Chen Y-FA, Hüls C, Gärtner K, Tagawa T, Mejias-Perez E, et al.

PLOS GENETICS

2021

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

cargoCD63cell-cell communicationdonor cellexosomesextracellular vesiclesmiRNAPKH26 membrane dyetarget cellsviral miRNAs

Chenyang Wang, Gongmin Zhu, Weiyang He, Hubin Yin, Fan Lin, Xin Gou and Xinyuan Li

The FASEB Journal

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesgum inflammationgum inflammation therapyM1 polarization of macrophagesmacrophagePDLSCperiodonitis therapyperiodontal diseaseperiodontal ligament stem cellperiodontitspolarization

Shengyang He MD, PhD, Duanni Chen MD, Mengyun Hu BS, Li Zhang MD, PhD, Caihong Liu MD et al.

Nanomedicine: Nanotechnology, Biology and Medicine

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Chronic lung diseaseCOPDepithelial-mesenchymal transitionexosomeextracellular vesiclesM2 macrophagesmiR-21small airway remodeling

Kunz, F., Kontopoulou, E., Reinhardt, K. et al.

Annals of Hematology

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesZeta Potential

Acute Myeloid Leukemiachildhood acute myeloid leukemiaextracellular vesiclesleukemia biomarkerspediatric AMLRNA

Hua Fang, Yutao Liu, Yaohong He, Yang Jiang, Yaping Wei, Han Liu, Yueqing Gong, Guangyu An

International Journal of Oncology

2019

ApplicationsBiomarkersCancerConcentration MeasurementExtracellular VesiclesLung AdenocarcinomaSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesLA biomarkerslung adenocarcinomalung adenocarcinoma biomarkerslung cancerlung cancer biomarkersmiR-382miR-486miR-505miRNAoncogenetargeted deliverytargeted EVs

Michelle L. Pleet, Catherine DeMarino, Spencer W. Stonier, John M. Dye, Steven Jacobson, M. Javad Amanand Fatah Kashanchi

Viruses

2019

ApplicationsConcentration MeasurementExtracellular VesiclesReviewSize MeasurementTechnical Nanoparticles

cytokineEbola virusEBOV protein VP40exosomeextracellular vesiclesglycoproteinGPNPnucleoprotein

Yu-Jing Zhang, Yang Han, Yu-Zhe Sun, Hang-Hang Jiang, Min Liu, Rui-Qun Qi, Xing-Hua Gao

Journal of Dermatological Science

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

extracellular vesiclesIL-6inflammatory cutaneous disorderkeratinocytemalassezia furfurmalassezia pathogenesismalassezia therapynuclear factor-kappa Bskin inflammation

Lei Zhang, Han Liu, Kai Xu, Zhixin Ling, Yeqing Huang, Qiang Hu, Kai Lu, Chunhui Liu et al.

International Journal of Biological Sciences

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

extracellular vesiclesHK2 cellsHPCHPC EVshypoxiaischaemiaischaemia-reperfusion injuryischaemic preconditioningkidney diseasemicroRNArenal injury

Lambros Kordelas, Esther Schwich, Robin Dittrich, Peter A. Horn, Dietrich W. Beelen, Verena Börger, Bernd Giebel and Vera Rebmann

International Journal of Molecular Sciences

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Acute InflammationCD4CD45RACD8EVsextracellular vesiclesgraft-versus-host-diseaseGvHDinflammation treatmentinflammation-associated disordersmesenchymal stem cellsmesenchymal stromal cellsMSCMSC-derived EVsMSC-EVssurface markers

Jung-Hyun Lee, Jochen Dindorf, Martin Eberhardt, Xin Lai, Christian Ostalecki, Nina Koliha, Stefani Gross,Katja Blume, Heiko Bruns, Stefan Wild, Gerold Schuler, Julio Vera, Andreas S Baur

Life Science Alliance

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

extracellular vesiclesmelanomamelanoma treatmentpEVsplasma-derived EVstumor development

H. A. Oliveiram A. Azevedo, J. Rubio

Mining, Metallurgy & Exploration

2019

ApplicationsConcentration MeasurementSize MeasurementTechnical NanoparticlesWater Analysis

extracellular vesicles

Schwager SC, Bordeleau F, Zhang J, Antonyak MA, Cerione RA, Reinhart-King C.

American Journal of Physiology. Cell Physiology

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesZeta Potential

cancer therapycancer treatmentcell contractilityextracellular matrixextracellular secreted vesicleextracellular vesiclesmechanotransductiontraction force

C DeMarino, ML Pleet, M Cowen, RA Barclay et al.

Scientific Reports

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesViruses

cART-altered EV contentCD63CD81CD9DemeclocyclineDoxycyclineextracellular vesiclesFDA-approved drugsHIV-1MethacyclineMinocyclinenon-coding viral RNAOxycyclineOxytetracyclineSCRT pathwayTAR RNtetracyclineVPS4

Lakhter A, Pratt RE, Moore RE, Doucette KK1, Maier BF, DiMeglio LA, Sims EK

Diabetologia

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Beta Cell Signal Transductioncaspasecell linescytokinediabetes biomarkerdiabetes predictiondiabetes preventionEVsexomiRexomiR-21extracellular vesicleshumanmicroRNAmiR-21miRNAtype 1 diabetes

Hanzi Xu, Zhen Gong, Yang Shen, Yichen Fang& Shanliang Zhong .

Epigenomics

2018

ApplicationsCancerConcentration MeasurementEndometrial CancerExosomesExtracellular VesiclesSize MeasurementVesicles

Circular RNAsdifferential circRNA expressionendometrial cancerexosomesextracellular vesiclesmiRNAstage III adenocarcinoma

C. Probert, T. Dottorini, A. Speakman, S. Hunt, T. Nafee, A. Fazeli, S. Wood, J. E. Brown & V. James

Oncogene

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesProstate CancerSize MeasurementTechnical NanoparticlesVesicles

cancer preventioncancer treatmentcell-cell communicationEV cargoEVsextracellular vesiclesPCaprostate cancerprostate cancer treatmenttargeted EVstumor derived exosomes

Nasibeh Karimi, Aleksander Cvjetkovic, Su Chul Jang, Rossella Crescitelli, Mohammad Ali Hosseinpour Feizi, Rienk Nieuwland, Jan Lötvall, Cecilia Lässer.

Cellular and Molecular Life Sciences

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Apo-A1CD63CD81CD9Density cushionexosomesextracellular vesiclesFlotillin-1LipoproteinsMass spectrometryPlasmaproteomicsSerumSize-exclusion chromatography

Pachler, Karin; Desgeorges, Alexandre; Folie, Christina; Mayr, Magdalena; Binder, Heide-Marie; et al.

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesF-NTAFluorescenceSize MeasurementTechnical NanoparticlesVesicles

AlexaFluor 488Antibody LabellingAntibody Stainingev characterizationEV quantificationEVsextracellular vesiclesf-NTAfluorescence NTAfluorescent labellingfNTAUCMSC-derived EVsumbilical cord mesenchymal stromal cells-derived EVs

Michelle L Pleet, James Erickson, Catherine DeMarino, Robert A Barclay, Maria Cowen, Benjamin Lepene, Janie Liang, Jens H Kuhn, Laura Prugar, Spencer W Stonier, John M Dye, Weidong Zhou, Lance A Liotta, M Javad Aman, Fatah Kashanchi

The Journal of Infectuos Diseases

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesViruses

Apoptosiscell cycleebola treatmentEbola virusEBOVEBOV pathogenesiEBOV treatmentEV biogenesisEVsextracellular vesiclesmonocyte apoptosispoptosis; cell cycleT cell apoptosisVP40

Kumar Subramani, Srikrishnan P. Raju, Xiaogang Chua, Marie Warren, Chirayu D. Pandyab, Nasrul Hoda, Sadanand Fulzele, Raghavan Raju

International Immunopharmacology

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

erythrocytesEV cargoexosomesextracellular vesiclesmicroRNAmiRNAmiRNA cargomultiple organ dysfunctionRBCsred blood cellsrheologysepsistissue hypoxiatissue perfusion

Phillip Munson, Ying-Wai Lam, Julie Dragon, Maximilian MacPherson and Arti Shukla.

The FASEB Journal

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Asbestos Exposure MesotheliomaCD81cell cyclechromosomal stabilityextracellular vesiclesgene expressionhuman mesothelia cellsproteomic cargoproteomicsTGFbtumorigenesis

Pu C, Huang H, Wang Z, Zou W, Lv Y, Zhou Z, Zhang Q, Qiao L, Wu F and Shao S

Frontiers in Physiology

2018

ApplicationsCancerConcentration MeasurementHepatocellular CarcinomaInstrument ComparisonSize MeasurementTechnical Nanoparticles

cancer biomarkerscancer diagnosiscancer therapyEVsextracellular vesiclesHCCHCC pathogenesishepatocellular carcinomamicroRNAmiR-144miR-21miR-21-5pmiRNAqRT-PCRsequencing analysisserum derived exosomes

Tan, E., Asada, H.H. & Ge, R.

Angiogenesis

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

AngiogenesisDLL4endothelial cellsextracellular vesiclesHUVECJA1-ICDJAG1NOTCH signallingproliferation

Shah N, Ishii M, Brandon C, Ablonczy Z, Cai J, Liu Y, Chou CJ, Rohrer B

Biochimica et biophysica acta. Molecular basis of disease

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Age-related Macular DegenerationEVsexosomesextracellular vesiclesHDAC6retinal pigment epitheliumRPERPE dysfunctiontight junctions

Jennifer Klump MD, Ulrike Phillipp, Marie Follo PhD, Anna Eremin MSc, Hannes Lehmann MD, Sigrun Nestel, Nikolas von Bubnoff Prof. Dr., Irina Nazarenko PD

Nanomedicine: Nanotechnology, Biology and Medicine

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

BRAFBRAF600Ecell-free circulating DNAcKITcKITD816VEV DNA contentextracellular vesiclesImatinibLiquid biopsymelanomapredictive biomarkersTherapy monitoringVemurafenib

Brandon M. Lehrich , Yaxuan Liang, Pooya Khosravi , Howard J. Federoff and Massimo S. Fiandaca

International Journal of Molecular Sciences

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Astrocyte Cell GrowthCMculture mediaEV isolationEV purificationEV-depletion methodsEVsexosomesextracellular vesiclesfetal bovine serumnanoparticle tracking analysis

Ruth E. Thomas , Evelyn S. Vincow, Gennifer E. Merrihew, Michael J. MacCoss, Marie Y. Davis, Leo J. Pallanck

PLOS GENETICS

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesGBAglucocerebrosidase deficiencyglucosylceramidase betaneurodegenerative diseases

Katherine A. Ruppert, Tin T. Nguyen, Karthik S. Prabhakara, Naama E. Toledano Furman, Amit K. Srivastava, Matthew T. Harting, Charles S. Cox Jr. & Scott D. Olson.

Scientific Reports - Nature

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD107CD63CD81CD9COX2/PGE2 pathwaycytokinesextracellular vesiclesinflammation attenuationinflammatory effectslocomotor recoverymesenchymal stromal cellsMicroglial ResponseSpinal Cord Injury

Joshua T. Smith, Benjamin H. Wunsch, Navneet Dogra et al.

Lab on a Chip

2018

ApplicationsBiomarkersConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

diagnosisdiagnostic biomarkerearly-stage disease diagnosisEV isolationEV purificationEV separationEVsextracellular vesiclesnanoDLDnanoscale deterministic lateral displacementtargeted deliverytargeted EVstreatment monitoring

J Rodrigues, CL Ramos, S Frases, RMC Godinho et al.

The Cell Surface

2018

ApplicationsConcentration MeasurementExtracellular VesiclesFungiSize MeasurementVesicles

Antifungal Developmentchitin metabolismchitin synthase geneschitinaseCryptococcus neoformansdeletionextracellular vesiclesglucuronoxylomannantargetvirulence

Ryan P. McNamara, Carolina P. Caro-Vegas, Lindsey M. Costantini

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

capto corecross-flowEV isolationEV purificationEVsextracellular vesiclesindustrial scale EV purificationindustrial scale EV-isolationtangential flow

Hyejong Kang, Myung-Ju Lee, Sang June Park and Myung-Shin Lee

International Journal of Molecular Sciences

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesgum inflammationgum inflammation therapyM1 polarization of macrophagesmacrophagePDLSCperiodonitis therapyperiodontal diseaseperiodontal ligament stem cellperiodontitspolarization

Xu Zhan , Shelley A. Deeke, Zhibin Ning, Amanda E. Starr, James et al.

Nature Communications

2018

ApplicationsConcentration MeasurementInstrument ComparisonSize MeasurementTechnical Nanoparticles

EVsexosomal biomarkersextracellular vesiclesgut microbiotaIBDIBD pathogenesisinflammatory bowel diseasemetaproteomics

Ryan P. McNamara, Lindsey M. Costantini, T. Alix Myers, Blake Schouest, Nicholas J. Maness, Jack D. Griffith, Blossom A. Damania, Andrew G. MacLean, Dirk P. Dittmer.

mBio

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesiclesViruses

AIDSCD4CD63CD81exosomesextracellular vesiclesFlotillinHIVlentivirusesmicrovesiclesNefSIV

Bremer, Michel; Ferrer-Tur, Rita; Görgens, André; Börger, Verena; Horn, Peter A; et al.

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesF-NTAFluorescenceSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesf-NTAflow cytometryfNTAnanoparticle characterizationnanoparticle measurementsingle EV detectionsingle particle analysissingle particle detection

Higginbotham, Samuel J; Hunt, Stuart; Lambert, Daniel W

Journal of Extracellular Vesicles

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CAFcancer associated fibroblastscancer cell-derived EVscancer progressionEV cargoEVsexosome cargoextracellular vesiclesfibroblast derived exosomesmicroRNAmiRNAmyofibroblast-derived exosomesmyofibroblastsNOFnormal oral fibroblastssolid tumortumor biomarkerstumor diagnosistumor prognosis

Ulrich H. Frey, Marina Klaassen, Crista Ochsenfarth, Florian Murke, Matthias Thielmann, Eva Kottenberg, Petra Kleinbongard, Stefanie Klenke, Andrea Engler, Gerd Heusch, Bernd Giebel. Jürgen Peters

Anaesthesiologica Scandinavica

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CABGcardioprotectioncardiovascular diseasescoronary aretery bypass surgeryEVsextracellular vesiclesmicroRNAmiRNAmyocardial ischaemia injurymyocardial reperfusion injuryremote ischaemic preconditioningRIPC

Sang June Park, Hyungtaek Jeon. Seung-Min Yoo, Myung-Shin Lee.

In Vitro Cellular & Developmental Biology - Animal

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

Biological Activityclinical applicationcomplement systemEV markersexpressionextracellular vesiclesstorage condition

Young Hwa Soung, Shane Ford, Cecilia Yan and Jun Chung

Cancers

2018

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

ARRDC3Arrestin Domain-containing 3Breast CancerBreast Cancer Therapycancer therapyendocytic recyclingEVsextracellular vesiclesintegrin β4ITG 4TNBCtriple-negative breast cancerubiquitination

AM da R Rondon, VH de Almeida, T Gomes et al.

Biochemical and Biophysical Research Communications

2018

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesMicrovesiclesSize MeasurementVesicles

Breast Cancercofilincytoskeletonextracellular vesiclesfasudilLIMKMDA-MB-231microvesiclesRhoA expressionROCKsilencingTissue factor

Karin Pachler, Nina Ketterl, Alexandre Desgeorges, Zsuzsanna A. Dunai, Sandra Laner-Plamberger, Doris Streif, Dirk Strunk, Eva Rohde and Mario Gimona

International Journal of Molecular Sciences

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

exosomesextracellular vesiclesimmune modulationmesenchymalT-cell proliferation

Huishan Guo, Maneka Chitiprolu, Luc Roncevic, Charlotte Javalet, Fiona J. Hemming, My Tran Trung, Lingrui Meng, Elyse Latreille, Christiano Tanese de Souza, Danielle McCulloch, R. Mitchell Baldwin, Rebecca Auer, Jocelyn Côté, Ryan Charles Russell, Rémy Sadoul, Derrick Gibbings

Developmental Cell

2017

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

AcidificationAtg5Autophagycancerendosomeexosomesextracellular vesiclesLC3multivesicular bodytumorV1V0-ATPase

JL Kang, J Park, SJ Gao, MS Lee.

Oncotarget

2017

ApplicationsConcentration MeasurementExtracellular VesiclesMicroparticlesSize MeasurementTechnical NanoparticlesVesiclesViruses

Alternative Complement PathwayCD63CD81complement systemendothelial cellsextracellular vesiclesherpesvirusHSP70innate immunityKSHVNF-κB pathwayproteomics analysis

S Huang, X Ge, J Yu, Z Han, Z Yin, Y Li, F Chen et al.

The FASEB Journal

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

Brain Derived Exosomesextracellular vesiclesglia cellsmiRNAmTOR signalingneuronal exosome transferneuronal inflammationPDE4Bpolarizationtraumatic brain injury

Verena Börger, Michel Bremer, Rita Ferrer-Tur, Lena Gockeln, Oumaima Stambouli, Amina Becic and Bernd Giebel

International Journal of Molecular Sciences

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

AlixAngiogenesisAnti-inflammatory CapabilitiesApoptosisCD63CD81CD9cell proliferationcell therapycytokinesexosomesextracellular vesiclesfibrosisimmunomodulationmesenchymal stem/stromal cellsmicrovesiclesneurogenesisoxidative stressTsg101

Déborah L.M. Ruperta, Virginia Claudio, Cecilia Lässer, Marta Bally

Biochimica et Biophysica Acta (BBA) - General Subjects

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesZeta Potential

Analytical MethodsBuoyant DensityCharacterizationexosomesextracellular vesiclesoptical propertiesPhysical propertiesQuantificationsizestructurevesicle subpopulations

Muhammad Nawaz, Farah Fatima and Jeremy A. Squire.

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases

2017

BiomarkersCancerExtracellular VesiclesVesicles

Analytical TechnologiesEV isolationexosomesexRNAextracellular vesiclesgenetic profilingLiquid biopsymetastasismiRNAnoninvasive diagnosis

Vera A. Tang, Tyler M. Renner, Anna K. Fritzsche, Dylan Burger & Marc-André Langlois.

Scientific Reports - Nature

2017

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesiclesVirusesZeta Potential

eGFPextracellular vesiclesHIVMoloney murine leukemia virusnanoscale flow cytometryRetrovirusSingle particle discriminationVirus-containing supernatant

Jung-Hyun Lee, Stephan Schierer, Katja Blume, Jochen Dindorf, Sebastian Wittki, Wei Xiang, et al.

eBioMedicine

2016

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

ADAM17ARTCD4Chronic HIV infectionextracellular vesiclesHIVHIV reservoirNefT-cellsVpu

Kordelas, L., Rebmann, V., Ludwig, A.-K., Radtke, S., Ruesing, Jl, Doeppner, T.R., Epple, M., Horn, P.A., Beelen, D.W., and Giebel, B.

Leukemia

2014

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD81conditioned mediaEV fractionexosomal markerextracellular vesiclesgraft-versus-host-diseaseimmune-modulating activitiesmicrovesiclesMSC-derived exosomesmultivesicular bodiesTsg101