Novel Therapy for Glioblastoma Multiforme by Restoring LRRC4 in Tumor Cells: LRRC4 Inhibits Tumor-Infitrating Regulatory T Cells by Cytokine and Programmed Cell Death 1-Containing Exosomes
Peiyao Li, Jianbo Feng, Yang Liu, Qiang Liu, Li Fan, Qing Liu, Xiaoling She, Changhong Liu, Tao Liu, Chunhua Zhao, Wei Wang, Guiyuan Li and Minghua Wu.
Frontiers in Immunology
2017
ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize Measurement
CCR4CD63CD81CD9exosomeGBM immune microenvironmentGlioblastomaHSP70LRRC4methylation-mediated LRRC4 inactivationmiRNA expressionprogrammed cell death 1regulatory T cellstumor-infiltrating lymphocytes
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