Tag: miRNA

Your search for miRNA returned 0 articles and 34 publications

Articles

Publications

Sequencing and bioinformatics analysis of miRNA from rat endplate chondrogenic exosomes

Chen, Xue-Wu; Li, Qiu-Wei; Wang, Hong

Exp Ther Med (Experimental and Therapeutic Medicine) 25 (6)

2023

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesmiRNASize MeasurementVesicles

epigeneticexosomeintervertebral disc degenerationmiRNA

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Human Bone Marrow Stromal Cell Exosomes Ameliorate Periodontitis

Yue, C.; Cao, J.; Wong, A.; Kim, J. H.; Alam, S.; Luong, G.; Talegaonkar, S.; Schwartz, Z.; Boyan, B. D.; Giannobile, W. V.; Sahingur, S. E.; Lin, Z.

Journal of dental research

2022

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

cell therapyexosomesexperimental periodontitishuman bone marrow stromal cellsmiRNAperiodontal inflammation

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Profiling Blood Serum Extracellular Vesicles in Plaque Psoriasis and Psoriatic Arthritis Patients Reveals Potential Disease Biomarkers

Lättekivi, Freddy; Guljavina, Irina; Midekessa, Getnet; Viil, Janeli; Heath, Paul R.; Bæk

International journal of molecular sciences

2022

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

Biomarkercirculating EVsmiRNApsoriatic arthritissurface proteome

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MicroRNA Candidate Biomarkers for Parkinson’s Disease and Idiopathic REM Sleep Behavior Disorder

Ligang Wu, Jun Liu, Yuanyuan Li, Ying Cao, Wei Liu, Hongdao Zhang, Aonan Zhao, Ningdi Luo

PREPRINT (Version 1) available at Research Square

2021

BiomarkersConcentration MeasurementExtracellular VesiclesParkinson's DiseaseSize MeasurementVesicles

EVsmall-seqidiopathic rapid eye movement sleep behavior disorder (iRBD)miRNAsncRNA

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MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells.

Albanese M, Chen Y-FA, Hüls C, Gärtner K, Tagawa T, Mejias-Perez E, et al.

PLOS GENETICS

2021

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

cargoCD63cell-cell communicationdonor cellexosomesextracellular vesiclesmiRNAPKH26 membrane dyetarget cellsviral miRNAs

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Changes of microRNAs expression profiles from red swamp crayfish (Procambarus clarkia) hemolymph exosomes in response to WSSV infection

HuiYang, XixiLi, Jiaojun Ji, ChunyouYuan, Xiaojian Gao, Yingying Zhang, Cheng Lu, Fenggang Li, Xiaojun Zhang

Fish & Shellfish Immunology

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesViruses

deep sequencingexosomeexosomesfishimmunologymicroRNAmiRNAP. clarkiaprocambarus clarkiashellfishWSSVWSSV virus

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Efficient isolation, biophysical characterisation and molecular composition of extracellular vesicles secreted by primary and immortalised cells of reproductive origin

Jamaludin NA, Thurston LM, Witek KJ, Meikle A, Basatvat S, Elliott S, Hunt S, Andronowska A, Fazeli A.

Theriogenology

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesZeta Potential

establishment of pregnancyEVs intercelllar communicationimmortalised cellsmicroRNAmiRNAoviductal epithelialprimary cellstheriogenology

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Exosomal miR-499a-5p promotes cell proliferation, migration and EMT via mTOR signaling pathway in lung adenocarcinoma

Lambros Kordelas, Esther Schwich, Robin Dittrich, Peter A. Horn, Dietrich W. Beelen, Shan He, Ziming Li, Yongfeng Yu, Qingyu Zeng, Yirui Cheng, Wenxiang Ji, Weiliang Xia, Shun Lu

Experimental Cell Research

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesLung CancerSize MeasurementTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer metastasiscarcinogenesisexosomal miRNAexosomeslung cancermicroRNAmiR499amiRNAmTOR pathwaytumor derived exosomes

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Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice

Huixin Zhang, Jin Wu, Jiahuan Wu, Qi Fan, Jingchao Zhou, Junwen Wu, Sichen Liu, Jie Zang, Jinhai Ye, Ming Xiao, Tian Tian and Jun Gao

Journal of Nanobiotechnology

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

AngiogenesisBrain Tissue Repaircerebral ischemiadrug deliveryendogenous delivery systemexosomesischemiaischemic strokemicroRNAmiR-210miRNAmiRNA deliverytargeted deliverytargeted EVs

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Exosomes derived from human umbilical cord mesenchymal stromal cells deliver exogenous miR-145-5p to inhibit pancreatic ductal adenocarcinoma progression

Yixuan Ding, Feng Cao, Haichen Sun, Yecheng Wang, Shuang Liu, Yanchuan Wu. Qingye Cui, Wen Tong Mei, Fei Li

Cancer Letters

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesPancreatic CancerSize MeasurementTechnical NanoparticlesVesicles

145-Exodeliverydrug deliveryexosomeshUCMSChuman umbilical cord mesenchymal stromal cellmicroRNAmiR-145miR-145-5pmiRNAmiRNA transferpancreatic ductal adenocarcinomaPDACtumor treatmentxenograft tumors

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Extracellular vesicle‑delivered miR‑505‑5p, as a diagnostic biomarker of early lung adenocarcinoma, inhibits cell apoptosis by targeting TP53AIP1

Hua Fang, Yutao Liu, Yaohong He, Yang Jiang, Yaping Wei, Han Liu, Yueqing Gong, Guangyu An

International Journal of Oncology

2019

ApplicationsBiomarkersCancerConcentration MeasurementExtracellular VesiclesLung AdenocarcinomaSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesLA biomarkerslung adenocarcinomalung adenocarcinoma biomarkerslung cancerlung cancer biomarkersmiR-382miR-486miR-505miRNAoncogenetargeted deliverytargeted EVs

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Genome-Wide, Integrative Analysis Implicates Exosome-Derived MicroRNA Dysregulation in Schizophrenia

Yang Du Yun, Yu Yang Hu, Xiao-Wan Li, Ze-Xu Wei, Rui-Yuan Pan, Xue-Song Li, Guang-En Zheng, Xiao-Yan Qin, Qing-Shan Liu

Schizophrenia Bulletin

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesZeta Potential

Brain-derived Neurotrophic Factorexosomal miRNAexosomeshsa-miR-206microRNAmiR-206miRNAmiRNA profilingschizophreniaschizophrenia biomarkersSCZSCZ biomarkersserum derived exosomes

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Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibit Endometrial Cancer Cell Proliferation and Migration through Delivery of Exogenous miR-302a

Xin Li, Li li Liu, Ju lei Yao, Kai Wang and Hao Ai

Stem Cells International

2019

ApplicationsCancerConcentration MeasurementEndometrial CancerExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Anticancer Therapyendometrial cancerendometrial cancer therapyengineered extracellular vesiclesEV engineeringhUCMSChuman umbilical cord mesenchymalstem cellsmicroRNAmiR-302amiRNAstem cellstumor suppressor miRNAtumor-targeting drug delivery

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Increased urinary exosomal microRNAs in children with idiopathic nephrotic syndrome

Tingting Chen, Cheng Wang, Hanqing Yu, Meng Ding, Cuiping Zhang, Xiaolan Lu, Chen-Yu Zhang, Chunni Zhang

eBioMedicine

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

exosomesillumina sequencing via synthesiskidney diseasekidney disease diagnosismicroRNAmiRNAnon-invasive biomarkerspaediatric idiopathic nephrotic syndromeRT-qPCRurinary exosomes

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Macrophage-Derived miRNA-Containing Exosomes Induce Peritendinous Fibrosis after Tendon Injury through the miR-21-5p/Smad7 Pathway

Haomin Cui, Yu He, Shuai Chen Deming Zhang, Yaling Yu, Cunyi Fan

Molecular Therapy - Nucleic Acids

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Bone Marrow Macrophageexosomeexosomeshand surgerymacrophage-derived exosomesmicroRNAmiR-21miR-21-5pmiRNAperitendinous adhesionperitendinous fibrosisperitendinous tissue fibrosisSmad7tendon adhesion preventiontendon adhesion treatmenttendon injurytendon-healing

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Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2.

Lu Chen, Le Chen, Zhiyuan Qin, Jinxiu Lei, Sheng Ye, Kui Zeng Hua Wang, Meidan Ying, Jianqing Gao, Su Zeng, Lushan Yu

Acta Pharmaceutica Sinica B

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesRenal Cell CarcinomaSize MeasurementTechnical NanoparticlesVesicles

epigenetic regulationmicroRANmiR-489miR-630miRNAOCT2OCT2 expressiononcotherapyoxaliplatinoxaliplatin resistanceRCCRCC treatmentrenal cancer treatmentrenal cell carcinoma

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Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes

Lakhter A, Pratt RE, Moore RE, Doucette KK1, Maier BF, DiMeglio LA, Sims EK

Diabetologia

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Beta Cell Signal TransductioncalreticulincaspaseCD63CD9cell linescytokinediabetes biomarkerdiabetes predictiondiabetes preventionEVsexomiRexomiR-21extracellular vesicleshumanmicroRNAmiR-21miRNAtype 1 diabetes

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Circular RNA expression in extracellular vesicles isolated from serum of patients with endometrial cancer

Hanzi Xu, Zhen Gong, Yang Shen, Yichen Fang& Shanliang Zhong .

Epigenomics

2018

ApplicationsCancerConcentration MeasurementEndometrial CancerExosomesExtracellular VesiclesSize MeasurementVesicles

Circular RNAsdifferential circRNA expressionendometrial cancerexosomesextracellular vesiclesmiRNAstage III adenocarcinoma

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Development of MSC-NTF cell exosomes for the treatment of neurodegenerative diseases

Kaspi, Haggai; Semo, Jonathan; Abramov, Natalie; Aricha, Revital.

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Anti-inflammatoryBBBBlood–Brain BarrierBone Marrow Derived Mesenchymal Stem Cellsdrug deliveryEV cargomicroRNAmiRNAMSCMSC-derived EVsMSC-EVsMSC-NTF cellsneurodegenerative diseasesneuronal growthnon-invasive therapytargeted deliverytargeted EVstargeted exosomes

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation

Camilo Rojas , Elena Barnaeva, Ajit G. Thomas, Xin Hu et al.

Scientific Reports

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Astrocyte-derived EVsBrain InflammationBrain InjurycytokineDPTIPEVsmicroRNAmiRNAneutral sphingomyeliinase 2nSMase2nSMase2 inhibition

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Effect of plasma-derived extracellular vesicles on erythrocyte deformability in polymicrobial sepsis

Kumar Subramani, Srikrishnan P. Raju, Xiaogang Chua, Marie Warren, Chirayu D. Pandyab, Nasrul Hoda, Sadanand Fulzele, Raghavan Raju

International Immunopharmacology

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

erythrocytesEV cargoexosomesextracellular vesiclesmicroRNAmiRNAmiRNA cargomultiple organ dysfunctionRBCsred blood cellsrheologysepsistissue hypoxiatissue perfusion

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Epigenetic modifications in hyperhomocysteinemia: potential role in diabetic retinopathy and age-related macular degeneration

Elmasry K, Mohamed R, Sharma I, Elsherbiny NM, Liu Y, Al-Shabrawey M, Tawfik A.

Oncotarget

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Age-related Macular DegenerationAngiogenesisBlood Retinal Barrierdiabetic retinopathyepigenetic modificationsGerotargethyperhomocysteinemiahypoxiainflammationmiRNAoxidative stress

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Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell prolife

X Dai, C Chen, Q Yang, J Xue, X Chen, B Sun, F Luo et al.

Cell Death & Disease

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

ArseniteArsenite-induced Carcinogenesiscell cyclecirculting RNAExosomal circRNA_100284exosomeslivermalignant transformationmiRNAproliferation

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Exosomal microRNA-21 derived from bronchial epithelial cells is involved in aberrant epithelium-fibroblast cross-talk in COPD induced by cigarette smoking

Xu H, Ling M, Xue J, Dai X, Sun Q, Chen C, Liu Y, Zhou L, Liu J, Luo F, Bian Q, Liu Q.

Theranostics

2018

ApplicationsConcentration MeasurementDiagnosticsExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Bronchial Epithelium-fibroblast Communicationcell-cell communicationchronic obstructive pulmonary diseasecigarette smoke induced COPDCOPDCOPD diagnosisCOPD treatmentCS-induced COPDEVs intercelllar communicationexosomesmicroRNAmiR-21miRNA

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Exosomal microRNAs derived from human amniotic epithelial cells accelerate wound healing by promoting the proliferation and migration of fibroblasts

Bin Zhao, Xiaodong Li, Xiaomin Shi, Xueqin Shi, Wei Zhang, Gaofeng Wu, Xujie Wang, Linlin Su, and Dahai Hu.

Stem Cells International

2018

ApplicationsConcentration MeasurementInstrument ComparisonSize MeasurementTechnical NanoparticlesZeta Potential

Accelerated Wound HealingCD63CD81CD9cell-cell communicationexosomal markersexosomal miRNAhAECshAECs-derived exosomeshuman amniotic epithelial cells-derived exosomesmicroRNAmiRNAmiRNA cargoprotein cargowound healing

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Extracellular Vesicle-Associated mir-21 and mir-144 Are Markedly Elevated in Serum of Patients With Hepatocellular Carcinoma.

Pu C, Huang H, Wang Z, Zou W, Lv Y, Zhou Z, Zhang Q, Qiao L, Wu F and Shao S

Frontiers in Physiology

2018

ApplicationsCancerConcentration MeasurementHepatocellular CarcinomaInstrument ComparisonSize MeasurementTechnical Nanoparticles

cancer biomarkerscancer diagnosiscancer therapyEVsextracellular vesiclesHCCHCC pathogenesishepatocellular carcinomamicroRNAmiR-144miR-21miR-21-5pmiRNAqRT-PCRsequencing analysisserum derived exosomes

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Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment

Shin La Shu, Yunchen Yang, Cheryl L. Allen, Orla Maguire, Hans Minderman et al.

Scientific Reports

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesMelanomaSize MeasurementTechnical NanoparticlesVesicles

cancer diagnosiscancer metastasiscancer therapyexosomesextracellular acidificationHADFHMEXhuman adult dermal fibroblastshuman melanoma-derived exosomesmetastasis developmentmetastasis promotionmicroRNAmiR-155miR-210miRNAmiRNA cargo

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Placental exosome-mediated Bta-miR-499-Lin28B/let-7 axis regulates inflammatory bias during early pregnancy

G Zhao, C Yang, J Yang, P Liu, K Jiang, A Shaukat et al.

Cell Death & Disease

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Abnormal Inflammatory BiasBta-miR-499CD63CD9exosomesLin28B/let-7 axismiRNANF-κBplacentapregnancy

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Probing the role of myofibroblast-derived extracellular vesicles in cancer

Higginbotham, Samuel J; Hunt, Stuart; Lambert, Daniel W

Journal of Extracellular Vesicles

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CAFcancer associated fibroblastscancer cell-derived EVscancer progressionEV cargoEVsexosome cargoextracellular vesiclesfibroblast derived exosomesmicroRNAmiRNAmyofibroblast-derived exosomesmyofibroblastsNOFnormal oral fibroblastssolid tumortumor biomarkerstumor diagnosistumor prognosis

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Receptor-Ligand Interaction Mediates Targeting of Endothelial Colony Forming Cell-derived Exosomes to the Kidney after Ischemic Injury

Jose L. Viñas, Matthew Spence, Alex Gutsol, William Knoll, Dylan Burger, Joseph Zimpelmann, David S. Allan2 & Kevin D. Burns

Scientific Reports

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

ECFC-derived exosomesendothelial colony forming cell-derived exosomesischaemia-reperfusion injuryischemic kidneyischemic kidney injurymicroRNAmiR-486miRNAtargeted EVs

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Remote ischaemic preconditioning increases serum extracellular vesicle concentrations with altered micro‐RNA signature in CABG patients

Ulrich H. Frey, Marina Klaassen, Crista Ochsenfarth, Florian Murke, Matthias Thielmann, Eva Kottenberg, Petra Kleinbongard, Stefanie Klenke, Andrea Engler, Gerd Heusch, Bernd Giebel. Jürgen Peters

Anaesthesiologica Scandinavica

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CABGcardioprotectioncardiovascular diseasescoronary aretery bypass surgeryEVsextracellular vesiclesmicroRNAmiRNAmyocardial ischaemia injurymyocardial reperfusion injuryremote ischaemic preconditioningRIPC

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Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons

S Huang, X Ge, J Yu, Z Han, Z Yin, Y Li, F Chen et al.

The FASEB Journal

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

Brain Derived Exosomesextracellular vesiclesglia cellsmiRNAmTOR signalingneuronal exosome transferneuronal inflammationPDE4Bpolarizationtraumatic brain injury

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Mining Extracellular Vesicles for Clinically Relevant Noninvasive Diagnostic Biomarkers in Cancer.

Muhammad Nawaz, Farah Fatima and Jeremy A. Squire.

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases

2017

BiomarkersCancerExtracellular VesiclesVesicles

Analytical TechnologiesEV isolationexosomesexRNAextracellular vesiclesgenetic profilingLiquid biopsymetastasismiRNAnoninvasive diagnosis

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Human mast cells release extracellular vesicle-associated DNA

Ganesh V Shelke, Su Chul Jang, Yanan Yin, Cecilia Lässer, Jan Lötv

matters

2016

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesZeta Potential

Aggregation of EVscargocell-free DNAEV fractionEV-associated DNAextracellular DNAmesenchymal stem cellsmiRNAmRNAnegative charge of the vesiclesretrotransposons

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