Tag: EVs

Your search for EVs returned 2 articles and 24 publications

Articles

graphic on storage conditions of extracellular vesicles (EVs)
Applications

Use of Fluorescence Nanoparticle Tracking Analysis as a tool for quality assessment of EVs

Correct and standardized storage conditions of extracellular vesicles (EVs) are essential prerequisites for the stability of clinical samples and the production of consistent EV batches for therapeutic use.
The loss of EV concentration due to improper storage conditions is associated with a reduced activity and physical integrity.
Check out our new app note on the importance of EV storage conditions and how fluorescence nanoparticle tracking analysis can be used as a quality assessment tool.

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27. June 2024

Publications

Biophysical and proteomic analyses of Pseudomonas syringae pv. tomato DC3000 extracellular vesicles suggest adaptive functions during plant infection

Janda, Martin; Rybak, Katarzyna; Krassini, Laura; Meng, Chen; Feitosa-Junior, Oséias; Stigliano, Egidio; Szulc, Beata; Sklenar, Jan; Menke, Frank L. H.; Malone, Jacob G.; Brachmann, Andreas; Klingl, Andreas; Ludwig, Christina; Robatzek, Silke

mBio

2023

ApplicationsConcentration MeasurementExtracellular VesiclesPathogeneSize MeasurementVesiclesZeta Potential

Arabidopsis thalianaEVsextracellular vesiclesnanoparticle tracking analysisNTApattern-triggered immunityproteomicsPTIPto DC3000

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Improved Wound Healing and Skin Regeneration Ability of 3,2′-Dihydroxyflavone-Treated Mesenchymal Stem Cell-Derived Extracellular Vesicles

Kim, Sehee; Shin, Yeokyung; Choi, Yujin; Lim, Kyung-Min; Jeong, Yeojin; Dayem, Ahmed Abdal; Lee, Yoonjoo; An, Jongyub; Song, Kwonwoo; Jang, Soo Bin; Cho, Ssang-Goo

IJMS (International Journal of Molecular Sciences) 24

2023

ApplicationsExosomesExtracellular VesiclesSize MeasurementVesicles

anti-inflammationEVsflavonoidMEK/ERK signalMSCswound healing

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BMSCs protect against renal ischemia-reperfusion injury by secreting exosomes loaded with miR-199a-5p that target BIP to inhibit endoplasmic reticulum stress at the very early reperfusion stages

Chenyang Wang, Gongmin Zhu, Weiyang He, Hubin Yin, Fan Lin, Xin Gou and Xinyuan Li

The FASEB Journal

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesgum inflammationgum inflammation therapyM1 polarization of macrophagesmacrophagePDLSCperiodonitis therapyperiodontal diseaseperiodontal ligament stem cellperiodontitspolarization

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Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells

Mengjie Zhao, Jinjin Xu, Shanliang Zhong, Yuchi Liu, Hong Xiao, Liangyuan Geng, Hongyi Liu

Oncology Reports

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

circRNAcircular RNAEVsglioma radioresistanceNor-EVsradioresistanceU251 cells

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Extracellular vesicle‑delivered miR‑505‑5p, as a diagnostic biomarker of early lung adenocarcinoma, inhibits cell apoptosis by targeting TP53AIP1

Hua Fang, Yutao Liu, Yaohong He, Yang Jiang, Yaping Wei, Han Liu, Yueqing Gong, Guangyu An

International Journal of Oncology

2019

ApplicationsBiomarkersCancerConcentration MeasurementExtracellular VesiclesLung AdenocarcinomaSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesLA biomarkerslung adenocarcinomalung adenocarcinoma biomarkerslung cancerlung cancer biomarkersmiR-382miR-486miR-505miRNAoncogenetargeted deliverytargeted EVs

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Individual Immune-Modulatory Capabilities of MSC-Derived Extracellular Vesicle (EV) Preparations and Recipient-Dependent Responsiveness

Lambros Kordelas, Esther Schwich, Robin Dittrich, Peter A. Horn, Dietrich W. Beelen, Verena Börger, Bernd Giebel and Vera Rebmann

International Journal of Molecular Sciences

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Acute InflammationCD4CD45RACD8EVsextracellular vesiclesgraft-versus-host-diseaseGvHDinflammation treatmentinflammation-associated disordersmesenchymal stem cellsmesenchymal stromal cellsMSCMSC-derived EVsMSC-EVssurface markers

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Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes

Lakhter A, Pratt RE, Moore RE, Doucette KK1, Maier BF, DiMeglio LA, Sims EK

Diabetologia

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Beta Cell Signal TransductioncalreticulincaspaseCD63CD9cell linescytokinediabetes biomarkerdiabetes predictiondiabetes preventionEVsexomiRexomiR-21extracellular vesicleshumanmicroRNAmiR-21miRNAtype 1 diabetes

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Communication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis.

C. Probert, T. Dottorini, A. Speakman, S. Hunt, T. Nafee, A. Fazeli, S. Wood, J. E. Brown & V. James

Oncogene

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesProstate CancerSize MeasurementTechnical NanoparticlesVesicles

cancer preventioncancer treatmentcell-cell communicationEV cargoEVsextracellular vesiclesPCaprostate cancerprostate cancer treatmenttargeted EVstumor derived exosomes

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Differential fluorescence nanoparticle tracking analysis for enumeration of the extracellular vesicle content in mixed particulate solutions

Pachler, Karin; Desgeorges, Alexandre; Folie, Christina; Mayr, Magdalena; Binder, Heide-Marie; et al.

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesF-NTAFluorescenceSize MeasurementTechnical NanoparticlesVesicles

AlexaFluor 488Antibody LabellingAntibody Stainingev characterizationEV quantificationEVsextracellular vesiclesf-NTAfluorescence NTAfluorescent labellingfNTAUCMSC-derived EVsumbilical cord mesenchymal stromal cells-derived EVs

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation

Camilo Rojas , Elena Barnaeva, Ajit G. Thomas, Xin Hu et al.

Scientific Reports

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Astrocyte-derived EVsBrain InflammationBrain InjurycytokineDPTIPEVsmicroRNAmiRNAneutral sphingomyeliinase 2nSMase2nSMase2 inhibition

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Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

Michelle L Pleet, James Erickson, Catherine DeMarino, Robert A Barclay, Maria Cowen, Benjamin Lepene, Janie Liang, Jens H Kuhn, Laura Prugar, Spencer W Stonier, John M Dye, Weidong Zhou, Lance A Liotta, M Javad Aman, Fatah Kashanchi

The Journal of Infectuos Diseases

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesViruses

Apoptosiscell cycleebola treatmentEbola virusEBOVEBOV pathogenesiEBOV treatmentEV biogenesisEVsextracellular vesiclesmonocyte apoptosispoptosis; cell cycleT cell apoptosisVP40

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Extracellular Vesicle-Associated mir-21 and mir-144 Are Markedly Elevated in Serum of Patients With Hepatocellular Carcinoma.

Pu C, Huang H, Wang Z, Zou W, Lv Y, Zhou Z, Zhang Q, Qiao L, Wu F and Shao S

Frontiers in Physiology

2018

ApplicationsCancerConcentration MeasurementHepatocellular CarcinomaInstrument ComparisonSize MeasurementTechnical Nanoparticles

cancer biomarkerscancer diagnosiscancer therapyEVsextracellular vesiclesHCCHCC pathogenesishepatocellular carcinomamicroRNAmiR-144miR-21miR-21-5pmiRNAqRT-PCRsequencing analysisserum derived exosomes

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Extracellular vesicle-mediated long-range communication in stressed retinal pigment epithelial cell monolayers

Shah N, Ishii M, Brandon C, Ablonczy Z, Cai J, Liu Y, Chou CJ, Rohrer B

Biochimica et biophysica acta. Molecular basis of disease

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Age-related Macular DegenerationEVsexosomesextracellular vesiclesHDAC6retinal pigment epitheliumRPERPE dysfunctiontight junctions

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Fetal Bovine Serum-Derived Extracellular Vesicles Persist within Vesicle-Depleted Culture Media

Brandon M. Lehrich , Yaxuan Liang, Pooya Khosravi , Howard J. Federoff and Massimo S. Fiandaca

International Journal of Molecular Sciences

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Astrocyte Cell GrowthCMculture mediaEV isolationEV purificationEV-depletion methodsEVsexosomesextracellular vesiclesfetal bovine serumnanoparticle tracking analysis

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Glucocerebrosidase deficiency promotes protein aggregation through dysregulation of extracellular vesicles

Ruth E. Thomas , Evelyn S. Vincow, Gennifer E. Merrihew, Michael J. MacCoss, Marie Y. Davis, Leo J. Pallanck

PLOS GENETICS

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesGBAglucocerebrosidase deficiencyglucosylceramidase betaneurodegenerative diseases

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Integrated Nanoscale Deterministic Lateral Displacement Arrays for Separation of Extracellular Vesicles from Clinically-Relevant Volumes of Biological Samples

Joshua T. Smith, Benjamin H. Wunsch, Navneet Dogra et al.

Lab on a Chip

2018

ApplicationsBiomarkersConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

diagnosisdiagnostic biomarkerearly-stage disease diagnosisEV isolationEV purificationEV separationEVsextracellular vesiclesnanoDLDnanoscale deterministic lateral displacementtargeted deliverytargeted EVstreatment monitoring

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Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles

Ryan P. McNamara, Carolina P. Caro-Vegas, Lindsey M. Costantini

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

capto corecross-flowEV isolationEV purificationEVsextracellular vesiclesindustrial scale EV purificationindustrial scale EV-isolationtangential flow

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Lipopolysaccharide-Preconditioned Periodontal Ligament Stem Cells Induce M1 Polarization of Macrophages through Extracellular Vesicles

Hyejong Kang, Myung-Ju Lee, Sang June Park and Myung-Shin Lee

International Journal of Molecular Sciences

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesgum inflammationgum inflammation therapyM1 polarization of macrophagesmacrophagePDLSCperiodonitis therapyperiodontal diseaseperiodontal ligament stem cellperiodontitspolarization

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Metaproteomics reveals associations between microbiome and intestinal extracellular vesicle proteins in pediatric inflammatory bowel disease

Xu Zhan , Shelley A. Deeke, Zhibin Ning, Amanda E. Starr, James et al.

Nature Communications

2018

ApplicationsConcentration MeasurementInstrument ComparisonSize MeasurementTechnical Nanoparticles

EVsexosomal biomarkersextracellular vesiclesgut microbiotaIBDIBD pathogenesisinflammatory bowel diseasemetaproteomics

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Phenotyping of EVs by multiwavelength fluorescence nanoparticle tracking Analysis

Bremer, Michel; Ferrer-Tur, Rita; Görgens, André; Börger, Verena; Horn, Peter A; et al.

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesF-NTAFluorescenceSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesf-NTAflow cytometryfNTAnanoparticle characterizationnanoparticle measurementsingle EV detectionsingle particle analysissingle particle detection

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Probing the role of myofibroblast-derived extracellular vesicles in cancer

Higginbotham, Samuel J; Hunt, Stuart; Lambert, Daniel W

Journal of Extracellular Vesicles

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CAFcancer associated fibroblastscancer cell-derived EVscancer progressionEV cargoEVsexosome cargoextracellular vesiclesfibroblast derived exosomesmicroRNAmiRNAmyofibroblast-derived exosomesmyofibroblastsNOFnormal oral fibroblastssolid tumortumor biomarkerstumor diagnosistumor prognosis

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Purification of extracellular vesicles from plasma by heparin-coated magnetic beads

Yiyao Huang; Dillon C. Muth; Lei Zheng; Kenneth W. Witwer

Journal of Extracellular Vesicles

2018

ApplicationsConcentration MeasurementExtracellular VesiclesTechnical NanoparticlesVesicles

EV isolationEV purificationEVsexosomesheparin-coated magnetic beadsosomesplasma derived exosomesplasma-derived EVs

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Remote ischaemic preconditioning increases serum extracellular vesicle concentrations with altered micro‐RNA signature in CABG patients

Ulrich H. Frey, Marina Klaassen, Crista Ochsenfarth, Florian Murke, Matthias Thielmann, Eva Kottenberg, Petra Kleinbongard, Stefanie Klenke, Andrea Engler, Gerd Heusch, Bernd Giebel. Jürgen Peters

Anaesthesiologica Scandinavica

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CABGcardioprotectioncardiovascular diseasescoronary aretery bypass surgeryEVsextracellular vesiclesmicroRNAmiRNAmyocardial ischaemia injurymyocardial reperfusion injuryremote ischaemic preconditioningRIPC

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The Role of Arrestin Domain-Containing 3 in Regulating Endocytic Recycling and Extracellular Vesicle Sorting of Integrin β4 in Breast Cancer

Young Hwa Soung, Shane Ford, Cecilia Yan and Jun Chung

Cancers

2018

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

ARRDC3Arrestin Domain-containing 3Breast CancerBreast Cancer Therapycancer therapyendocytic recyclingEVsextracellular vesiclesintegrin β4ITG 4TNBCtriple-negative breast cancerubiquitination

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