Category: Cancer

Sun, Yifan; Li, Miao; Zhang, Xiaoshan; Xu, Dongjie; Wu, Jie; Gu, Xinrui; Khan, Adeel; Shen, Han; Li, Zhiyang

BMC Cancer

2023

ApplicationsBiomarkersCancerConcentration MeasurementDiagnosticsExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesVesicles

Double-stranded DNANucleic acid to protein ratioSmall extracellular vesiclestumor diagnosis

Sanwlani, Rahul; Kang, Taeyoung; Gummadi, Sriram; Nedeva, Christina; Ang, Ching-Seng; Mathivanan, Suresh

Proteomics

2023

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

bovine milk-derived extracellular vesiclescancer chemotherapydietary extracellular vesiclesspecies crosstalkstat signallingtriple-negative breast cancer

Ben, Suqin; Huang, Xiulin; Shi, Yongxin; Xu, Ziheng; Xiao, Hui

Cell communication and signaling : CCS 21 (1)

2023

ApplicationsCancerExosomesExtracellular VesiclesLung CancerSize MeasurementVesicles

cancer associated coagulation disorderscancer-associated thrombosisexosomeslung cancerMast cells

Shen, Shizhen; Shen, Zhangjin; Wang, Conghui; Wu, Xiaodong; Wang, Lingfang; Ye, Lele; Zhang, Songfa; Cheng, Xiaodong

iScience

2023

ApplicationsCancerConcentration MeasurementExtracellular VesiclesOvarian CancerVesicles

epithelial ovarian cancerextracellular vesicleslysate -80°C storagetissue -80°C storage

Wang, Ziyuan; Zhang, Chen; Guo, Jian; Wang, Wei; Si, Qin; Chen, Chong; Luo, Yunping; Duan, Zhaojun

Translational Oncology

2023

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Cbx5exosomesmetastasismiR-223-3pTAMs

Di Xu; Liu, Zhen; Liang, Ming-Xing; Chen, Wen-Quan; Fei, Yin-Jiao; Yang, Su-Jin; Wu, Yang; Zhang, Wei; Tang, Jin-Hai

Discover. Oncology 14 (1)

2023

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

exosomesHeat shock protein family B (small) member 8 (HSPB8)hyperthermiaM1 macrophages polarizationtriple-negative breast cancer

Li, Jun; Bao, Yongjie; Peng, Sisi; Jiang, Chao; Zhu, Luying; Zou, Sihai; Xu, Jie; Li, Yong

CIMB (Current Issues in Molecular Biology)

2023

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

exosomeM2 macrophagesmacrophagesMiR-23a-3pOSCCPTEN

Tengler, Luisa; Schütz, Julia; Tiedtke, Moritz; Jablonska, Jadwiga; Theodoraki, Marie-Nicole; Nitschke, Katja; Weiß, Christel; Seiz, Elena; Affolter, Annette; Jungbauer, Frederic; Lammert, Anne; Rotter, Nicole; Ludwig, Sonja

Molecular Medicine

2023

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesVesicles

Angiogenesisendothelial cellsexosomesHead and neck cancerPlasmaSmall extracellular vesicles

Jordaens, Stephanie; Oeyen, Eline; Willems, Hanny; Ameye, Filip; Wachter, Stefan de; Pauwels, Patrick; Mertens, Inge

Biomolecules

2023

ApplicationsBiomarkersCancerConcentration MeasurementExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesVesicles

Biomarkerextracellular vesiclesLiquid biopsynon-muscle-invasive bladder cancer (NMIBC)oncologyproteomicsurine

Fang, Yu; Wu, Feng; Shang, Guoyin; Yin, Changqing

Genomics

2023

ApplicationsCancerColorectal CancerExosomesExtracellular VesiclesSize MeasurementVesicles

Bone marrow stromal cellcolorectal cancerexosomesPI3K/AktSCARA5

Yuan D, Guo T, Zhu D, Ge H, Zhao Y, Huang A, Wang X, Cao X, He C, Qian H, Yu H

Cancer Management and Research

2022

ApplicationsCancerExosomesExtracellular VesiclesOvarian CancerSize MeasurementVesicles

lncRNATumor microenvironment

Giulia Furesi, Antonio Miguel de Jesus Domingues, Dimitra Alexopoulou, Andreas Dahl 3, Matthias Hackl Johannes R. Schmidt, Stefan Kalkhof Thomas Kurth, Hanna Taipaleenmäki, Stefanie Conrad, Christine Hofbauer, Martina Rauner and Lorenz C. Hofbauer

International Journal of Molecular Sciences

2022

ApplicationsCancerConcentration MeasurementProstate CancerSize Measurement

exosomal miRNAmetastasesosteoprogenitors

Faith H N Howard, Haider Al-Janabi, Priya Patel, Katie Cox, Emily Smith, Jayakumar Vadakekolathu, A. Graham Pockley, Joe Conner, James F Nohl, Dan A Allwood, Cristal Collado-Rojas, Aneurin Kennerley, Sarah Staniland, and Munitta Muthana

Small Journal

2022

CancerDrug DeliveryZeta Potential

Bacterial Derived Nanomagnetsoncolytic viruses

Petra J. Pederson, Huiyun Liang, Daria Filonov, Susan L. Mooberry

Cancers

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

eribulinexosomesextracellular vesiclesmicrotubule targeting agentsmicrovesicles

Lei Xi, Meixi Peng, Shuiqing Liu, Yongcan Liu, Xueying Wan, Yixuan Hou, Yilu Qin, Liping Yang, Shanchun Chen, Huan Zeng, Yong Teng, Xiaojiang Cui, Manran Liu

Journal of Extracellular Vesicles

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Autophagy-associated Exosome ReleaseBreast CancerCAF derived exosomescancer associated fibroblastsfibroblast derived exosomestumor developmenttumor progression

Karan M. Shah, Luke Tattersall, Aleana Hussain, Sarah C. Macfarlane, Alexander Williamson, Adelina E. Acosta-Martin, Janine T. Erler, Penelope D. Ottewell, Alison Gartland

bioRxiv

2021

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesMetastasisSize MeasurementVesicles

intra-tumoral hypoxiaP2RX7

Liu Yang, Xuedong Tong, Yong Zhang, Yan Li, Jiangwei Liu, Ruiling Yin, Dong Zeng, Yue Yuan, and Kun Deng

Advanced Materials Technology

2021

BiomarkersCancerConcentration MeasurementExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesVesicles

pan-cancer screeningPhosphatidylserine

Meixi Peng, Jun Ren, Yipei Jing, Xueke Jiang, Qiaoling Xiao, Junpeng Huang, Yonghong Tao, Li Lei, Xin Wang, Zailin Yang, Zesong Yang, Qian Zhan, Can Lin, Guoxiang Jin, Xian Zhang, Ling Zhang

Journal of Extracellular Vesicles

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD63paclitaxeltetraspanintriple-negative breast cancervinorelbine

Lin-Li Lv, Ye Feng, Min Wu, Bin Wang, Zuo-Lin Li, Xin Zhong, Wei-Jun Wu et al.

Cell Death & Differentiation

2020

BiomarkersCancerExosomesExtracellular VesiclesGastro-Esophageal AdenocarcinomaVesicles

Acute Kidney Injurychronic kidney injurychronic proteinuric kidney diseaseeGPC3exosoml miRNAsGlypican 3GPC3insterstitial inflammationkidney disease therapymicroRNAmiRNAsrenal exosomesTECTEC derived exosomestubular epithelial cellstubulointerstitial inflammation

Meiling Gao, Fang He, Bin-Cheng Yin and Bang-Ce Ye

Analyst

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer metastasiscancer prognosiscancer therapycancer treatmentCD63CD63 aptamerdendrimerexosome detectionmagnetic beadstumor biomarkerstumor derived exosomestumor development

Zhen Zhang, Chuanhao Tang, Libo Zhao, Li Xu, Wei Zhou, Zaizai Dong, Yuqing Yang, Qiqi Xiec and Xiaohong Fang

Nanoscale

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer treatmentexosome identificationexosome quantificationexosomes in human plasmanon-invasive cancer diagnosisplasma derived exosomestumor derived exosomes

Qian Yang, Yao Xiao, Yanlong Yin, Gaoyin Li, Jinrong Peng

Molecular Pharmaceutics

2019

ApplicationsBreast CancerCancerConcentration MeasurementDrug DeliveryExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Breast Cancer Therapycancer therapycombination therapydrug deliverydual drug-loaded nanoparticlesdual model imaginglong circulationnanoparticle drug-loadingphoto-chemo combination therapytumor phototherapytumor-targeting drug delivery

Hui-Ying Hu, Chen-Huan Yu, Huan-Huan Zhang, Song-Zhao Zhang, Wen-Ying Yu. Yang, Yang, Qin Chen

International Journal of Biological Macromolecules

2019

ApplicationsBiomarkersCancerColorectal CancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Angiogenesiscancer biomarkerscolorectal cancerCRCCRC angiogenesisCRC-derived exosomesdiagnostic biomarkerexomiRexomiR-1229exosomal biomarkersexosomal miRNATumor microenvironmentVEGFVEGF pathway

Lambros Kordelas, Esther Schwich, Robin Dittrich, Peter A. Horn, Dietrich W. Beelen, Shan He, Ziming Li, Yongfeng Yu, Qingyu Zeng, Yirui Cheng, Wenxiang Ji, Weiliang Xia, Shun Lu

Experimental Cell Research

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesLung CancerSize MeasurementTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer metastasiscarcinogenesisexosomal miRNAexosomeslung cancermicroRNAmiR499amiRNAmTOR pathwaytumor derived exosomes

Yixuan Ding, Feng Cao, Haichen Sun, Yecheng Wang, Shuang Liu, Yanchuan Wu. Qingye Cui, Wen Tong Mei, Fei Li

Cancer Letters

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesPancreatic CancerSize MeasurementTechnical NanoparticlesVesicles

145-Exodeliverydrug deliveryexosomeshUCMSChuman umbilical cord mesenchymal stromal cellmicroRNAmiR-145miR-145-5pmiRNAmiRNA transferpancreatic ductal adenocarcinomaPDACtumor treatmentxenograft tumors

Shihua Wang, Xiaodong Su, Meiqian Xu, Xian Xiao, Xiaoxia Li, Hongling Li, Armand Keating, and Robert Chunhua Zhao

Stem Cell Research & Therapy

2019

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

AdipocyteAdipocyte ExosomesBreast Cancercell-cell communicationexosomeshippo signaling pathwaymesenchymal stromal/stem celltumor development

Mohammad Rahbari, Mathieu Pecqueux, Daniela Aust, Holger Stephan, Oliver Tiebel, Antonios Chatzigeorgiou, Torsten Tonn, Franziska Baenke et al.

Journal of Clinical Medicine

2019

BiomarkersCancerExosomesExtracellular VesiclesGastro-Esophageal AdenocarcinomaVesicles

diagnostic biomarkereGPC3Glypican 3GPC3

Hua Fang, Yutao Liu, Yaohong He, Yang Jiang, Yaping Wei, Han Liu, Yueqing Gong, Guangyu An

International Journal of Oncology

2019

ApplicationsBiomarkersCancerConcentration MeasurementExtracellular VesiclesLung AdenocarcinomaSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesLA biomarkerslung adenocarcinomalung adenocarcinoma biomarkerslung cancerlung cancer biomarkersmiR-382miR-486miR-505miRNAoncogenetargeted deliverytargeted EVs

Xin Li, Li li Liu, Ju lei Yao, Kai Wang and Hao Ai

Stem Cells International

2019

ApplicationsCancerConcentration MeasurementEndometrial CancerExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Anticancer Therapyendometrial cancerendometrial cancer therapyengineered extracellular vesiclesEV engineeringhUCMSChuman umbilical cord mesenchymalstem cellsmicroRNAmiR-302amiRNAstem cellstumor suppressor miRNAtumor-targeting drug delivery

Schwager SC, Bordeleau F, Zhang J, Antonyak MA, Cerione RA, Reinhart-King C.

American Journal of Physiology. Cell Physiology

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesZeta Potential

cancer therapycancer treatmentcell contractilityextracellular matrixextracellular secreted vesicleextracellular vesiclesmechanotransductiontraction force

Qingyu Zeng, Shibin Hong, Xue Wang, Yirui Cheng, Junfeng Sun, Weiliang Xia

Experimental Cell Research

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesLung CancerSize MeasurementTechnical NanoparticlesVesicles

exosome-related diseasesexosomesLIPUSLIPUS/exosome interactionLow-intensity pulsed ultrasoundmTOR

Lu Chen, Le Chen, Zhiyuan Qin, Jinxiu Lei, Sheng Ye, Kui Zeng Hua Wang, Meidan Ying, Jianqing Gao, Su Zeng, Lushan Yu

Acta Pharmaceutica Sinica B

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesRenal Cell CarcinomaSize MeasurementTechnical NanoparticlesVesicles

epigenetic regulationmicroRANmiR-489miR-630miRNAOCT2OCT2 expressiononcotherapyoxaliplatinoxaliplatin resistanceRCCRCC treatmentrenal cancer treatmentrenal cell carcinoma

L Simón-Gracia, P Scodeller, SS Fuentes, V Gómez et al.

Oncotarget

2018

ApplicationsBreast CancerCancerConcentration MeasurementPolymersomesVesicles

LinTT1p32PETpolyethylene glycol-polycaprolactonepolymersomesprecision-guided tumor imagingtriple-negative breast cancertumortumor-associated macrophagestumor-penetrating peptide

Hanzi Xu, Zhen Gong, Yang Shen, Yichen Fang& Shanliang Zhong .

Epigenomics

2018

ApplicationsCancerConcentration MeasurementEndometrial CancerExosomesExtracellular VesiclesSize MeasurementVesicles

Circular RNAsdifferential circRNA expressionendometrial cancerexosomesextracellular vesiclesmiRNAstage III adenocarcinoma

C. Probert, T. Dottorini, A. Speakman, S. Hunt, T. Nafee, A. Fazeli, S. Wood, J. E. Brown & V. James

Oncogene

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesProstate CancerSize MeasurementTechnical NanoparticlesVesicles

cancer preventioncancer treatmentcell-cell communicationEV cargoEVsextracellular vesiclesPCaprostate cancerprostate cancer treatmenttargeted EVstumor derived exosomes

Dan Jin, Fan Yang, Yulin Zhang, Li Liu, Yujuan Zhou, Fubing Wang, and Guo-Jun Zhang

Analytical Chemistry

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

cancer diagnosisExoAppexosome-oriented aptamer nanoprobeexosomestargeted EVstumor derived exosomes

Pu C, Huang H, Wang Z, Zou W, Lv Y, Zhou Z, Zhang Q, Qiao L, Wu F and Shao S

Frontiers in Physiology

2018

ApplicationsCancerConcentration MeasurementHepatocellular CarcinomaInstrument ComparisonSize MeasurementTechnical Nanoparticles

cancer biomarkerscancer diagnosiscancer therapyEVsextracellular vesiclesHCCHCC pathogenesishepatocellular carcinomamicroRNAmiR-144miR-21miR-21-5pmiRNAqRT-PCRsequencing analysisserum derived exosomes

Shin La Shu, Yunchen Yang, Cheryl L. Allen, Orla Maguire, Hans Minderman et al.

Scientific Reports

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesMelanomaSize MeasurementTechnical NanoparticlesVesicles

cancer diagnosiscancer metastasiscancer therapyexosomesextracellular acidificationHADFHMEXhuman adult dermal fibroblastshuman melanoma-derived exosomesmetastasis developmentmetastasis promotionmicroRNAmiR-155miR-210miRNAmiRNA cargo

Higginbotham, Samuel J; Hunt, Stuart; Lambert, Daniel W

Journal of Extracellular Vesicles

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CAFcancer associated fibroblastscancer cell-derived EVscancer progressionEV cargoEVsexosome cargoextracellular vesiclesfibroblast derived exosomesmicroRNAmiRNAmyofibroblast-derived exosomesmyofibroblastsNOFnormal oral fibroblastssolid tumortumor biomarkerstumor diagnosistumor prognosis

Yang, Y., Zhang, L., La, X. et al. Jürgen Peters

Naunyn-Schmiedeberg's Archives of Pharmacology

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

AngiogenesisAntiangiogenesisdrug resistanct cancer cellsexosomesglucose-regulated protein 78GRP78interactionSAAsalvianolic acid Asalvianolic acidATCMtraditional chinese medicinetumor developmenttumor-secreted GRP78

MKS Tang, PYK Yue, PP Ip, RL Huang, HC Lai et al.

Nature Communications

2018

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesOvarian CancerSize MeasurementVesicles

AsciteBiomarkerE-cadherinexosomesHUVECNFκB signalingovarian cancersE-cadtumor angiogenesisβ-catenin

Young Hwa Soung, Shane Ford, Cecilia Yan and Jun Chung

Cancers

2018

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

ARRDC3Arrestin Domain-containing 3Breast CancerBreast Cancer Therapycancer therapyendocytic recyclingEVsextracellular vesiclesintegrin β4ITG 4TNBCtriple-negative breast cancerubiquitination

AM da R Rondon, VH de Almeida, T Gomes et al.

Biochemical and Biophysical Research Communications

2018

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesMicrovesiclesSize MeasurementVesicles

Breast Cancercofilincytoskeletonextracellular vesiclesfasudilLIMKMDA-MB-231microvesiclesRhoA expressionROCKsilencingTissue factor

Huishan Guo, Maneka Chitiprolu, Luc Roncevic, Charlotte Javalet, Fiona J. Hemming, My Tran Trung, Lingrui Meng, Elyse Latreille, Christiano Tanese de Souza, Danielle McCulloch, R. Mitchell Baldwin, Rebecca Auer, Jocelyn Côté, Ryan Charles Russell, Rémy Sadoul, Derrick Gibbings

Developmental Cell

2017

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

AcidificationAtg5Autophagycancerendosomeexosomesextracellular vesiclesLC3multivesicular bodytumorV1V0-ATPase

FG Gomes, V Sandim, VH Almeida, AMR Rondon.

Thrombosis Research

2017

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

AggregationBreast Cancer Derived EVscancer-associated thrombosisMCF-7 EVsMDA-MB-231 EVsplasma coagulationplatelet activationthrombin generationTissue factor

Chun-Jung Lin, Andrew Dang, Elizabeth Hernandez, Jer-Tsong Hsieh

Cancer Research

2017

ApplicationsCancerConcentration MeasurementInstrument ComparisonProstate CancerSize MeasurementTechnical Nanoparticles

cancer treatmentcastration-resistant prostate cancerchemoresistanceCRPCCRPC treatment resistancePCaprognostic biomarkerprostate cancerprostate cancer treatmenttargeted deliverytargeted EVstargeted exosomesTDEtherapeutic targettumor derived exosomes

Dong Uk Kim, Francis A San Lucas, Matthew Cagley, Bret Stephens, Feven C Mulu, Jonathan Castillo, Vincent Bernard, Gauri R. Varadhachary, Matthew H. G. Katz, Hector A Alvarez, Anirban Maitra;

Journal of Clinical Oncology

2017

ApplicationsCancerConcentration MeasurementExtracellular VesiclesPancreatic CancerSize MeasurementVesicles

Bioactive MoleculesBiomarkerLiquid biopsymetastatispancreatic cancerPDACpredictorstumor progression

Muhammad Nawaz, Farah Fatima and Jeremy A. Squire.

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases

2017

BiomarkersCancerExtracellular VesiclesVesicles

Analytical TechnologiesEV isolationexosomesexRNAextracellular vesiclesgenetic profilingLiquid biopsymetastasismiRNAnoninvasive diagnosis

Ágota Tűzesi, Teresia Kling, Anna Wenger, Taral R. Lunavat, Su Chul Jang, Bertil Rydenhag, Jan Lötvall, Steven M. Pollard, Anna Danielsson, Helena Carén.

Oncotarget

2017

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

Braincancer stem cellsexosomesgene expressiongliomaGlioma stem cellmicroRNAmRNA expressionneural stem cellpediatric

Estibaliz Alegre, Vera Rebmann, Joel Lemaoult, Carmen Rodriguez, Peter A Horn, Angel Díaz-Lagares, José I Echeveste, Alvaro González

European Journal of Immunology

2013

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD63circulating HLA-G complexesexosomeshuman leukocyte antigen-G (HLA-G)markermicrovesiclesNK cellstumor spreadingUbiquitin