Category: Cancer

Your search for Cancer returned 0 articles and 40 publications

Articles

Publications

Exosomal lncRNA ATB Derived from Ovarian Cancer Cells Promotes Angiogenesis via Regulating miR-204-3p/TGFβR2 Axis

Yuan D, Guo T, Zhu D, Ge H, Zhao Y, Huang A, Wang X, Cao X, He C, Qian H, Yu H

Cancer Management and Research

2022

ApplicationsCancerExosomesExtracellular VesiclesOvarian CancerSize MeasurementVesicles

lncRNATumor microenvironment

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Exosomal miRNAs from Prostate Cancer Impair Osteoblast Function in Mice

Giulia Furesi, Antonio Miguel de Jesus Domingues, Dimitra Alexopoulou, Andreas Dahl 3, Matthias Hackl Johannes R. Schmidt, Stefan Kalkhof Thomas Kurth, Hanna Taipaleenmäki, Stefanie Conrad, Christine Hofbauer, Martina Rauner and Lorenz C. Hofbauer

International Journal of Molecular Sciences

2022

ApplicationsCancerConcentration MeasurementProstate CancerSize Measurement

exosomal miRNAmetastasesosteoprogenitors

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Nanobugs as Drugs: Bacterial Derived Nanomagnets Enhance Tumor Targeting and Oncolytic Activity of HSV-1 Virus

Faith H N Howard, Haider Al-Janabi, Priya Patel, Katie Cox, Emily Smith, Jayakumar Vadakekolathu, A. Graham Pockley, Joe Conner, James F Nohl, Dan A Allwood, Cristal Collado-Rojas, Aneurin Kennerley, Sarah Staniland, and Munitta Muthana

Small Journal

2022

CancerDrug DeliveryZeta Potential

Bacterial Derived Nanomagnetsoncolytic viruses

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Eribulin and Paclitaxel Differentially Alter Extracellular Vesicles and Their Cargo from Triple-Negative Breast Cancer Cells

Petra J. Pederson, Huiyun Liang, Daria Filonov, Susan L. Mooberry

Cancers

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

eribulinexosomesextracellular vesiclesmicrotubule targeting agentsmicrovesicles

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Hypoxia-stimulated ATM activation regulates autophagy-associated exosome release from cancer-associated fibroblasts to promote cancer cell invasion

Lei Xi, Meixi Peng, Shuiqing Liu, Yongcan Liu, Xueying Wan, Yixuan Hou, Yilu Qin, Liping Yang, Shanchun Chen, Huan Zeng, Yong Teng, Xiaojiang Cui, Manran Liu

Journal of Extracellular Vesicles

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Autophagy-associated Exosome ReleaseBreast CancerCAF derived exosomescancer associated fibroblastsfibroblast derived exosomestumor developmenttumor progression

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P2RX7 inhibition reduces breast cancer induced osteolytic lesions – implications for bone metastasis

Karan M. Shah, Luke Tattersall, Aleana Hussain, Sarah C. Macfarlane, Alexander Williamson, Adelina E. Acosta-Martin, Janine T. Erler, Penelope D. Ottewell, Alison Gartland

bioRxiv

2021

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesMetastasisSize MeasurementVesicles

intra-tumoral hypoxiaP2RX7

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Tim4-Functionalized HBEV-Chip by Isolating Plasma-Derived Phosphatidylserine-Positive Small Extracellular Vesicles for Pan-Cancer Screening

Liu Yang, Xuedong Tong, Yong Zhang, Yan Li, Jiangwei Liu, Ruiling Yin, Dong Zeng, Yue Yuan, and Kun Deng

Advanced Materials Technology

2021

BiomarkersCancerConcentration MeasurementExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesVesicles

pan-cancer screeningPhosphatidylserine

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Tumour-derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8-mediated creatine import in NPM1-mutated acute myeloid leukaemia

Meixi Peng, Jun Ren, Yipei Jing, Xueke Jiang, Qiaoling Xiao, Junpeng Huang, Yonghong Tao, Li Lei, Xin Wang, Zailin Yang, Zesong Yang, Qian Zhan, Can Lin, Guoxiang Jin, Xian Zhang, Ling Zhang

Journal of Extracellular Vesicles

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD63paclitaxeltetraspanintriple-negative breast cancervinorelbine

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Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury.

Lin-Li Lv, Ye Feng, Min Wu, Bin Wang, Zuo-Lin Li, Xin Zhong, Wei-Jun Wu et al.

Cell Death & Differentiation

2020

BiomarkersCancerExosomesExtracellular VesiclesGastro-Esophageal AdenocarcinomaVesicles

Acute Kidney Injurychronic kidney injurychronic proteinuric kidney diseaseeGPC3exosoml miRNAsGlypican 3GPC3insterstitial inflammationkidney disease therapymicroRNAmiRNAsrenal exosomesTECTEC derived exosomestubular epithelial cellstubulointerstitial inflammation

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A dual signal amplification method for exosome detection based on DNA dendrimer self-assembly.

Meiling Gao, Fang He, Bin-Cheng Yin and Bang-Ce Ye

Analyst

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer metastasiscancer prognosiscancer therapycancer treatmentCD63CD63 aptamerdendrimerexosome detectionmagnetic beadstumor biomarkerstumor derived exosomestumor development

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Aptamer-based fluorescence polarization assay for separation-free exosome quantification

Zhen Zhang, Chuanhao Tang, Libo Zhao, Li Xu, Wei Zhou, Zaizai Dong, Yuqing Yang, Qiqi Xiec and Xiaohong Fang

Nanoscale

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer treatmentexosome identificationexosome quantificationexosomes in human plasmanon-invasive cancer diagnosisplasma derived exosomestumor derived exosomes

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Erythrocyte Membrane-camouflaged IR780 and DTX co-loading Polymeric Nanoparticles for Imaging-guided Cancer Photo-Chemo Combination Therapy

Qian Yang, Yao Xiao, Yanlong Yin, Gaoyin Li, Jinrong Peng

Molecular Pharmaceutics

2019

ApplicationsBreast CancerCancerConcentration MeasurementDrug DeliveryExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Breast Cancer Therapycancer therapycombination therapydrug deliverydual drug-loaded nanoparticlesdual model imaginglong circulationnanoparticle drug-loadingphoto-chemo combination therapytumor phototherapytumor-targeting drug delivery

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Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2

Hui-Ying Hu, Chen-Huan Yu, Huan-Huan Zhang, Song-Zhao Zhang, Wen-Ying Yu. Yang, Yang, Qin Chen

International Journal of Biological Macromolecules

2019

ApplicationsBiomarkersCancerColorectal CancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Angiogenesiscancer biomarkerscolorectal cancerCRCCRC angiogenesisCRC-derived exosomesdiagnostic biomarkerexomiRexomiR-1229exosomal biomarkersexosomal miRNATumor microenvironmentVEGFVEGF pathway

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Exosomal miR-499a-5p promotes cell proliferation, migration and EMT via mTOR signaling pathway in lung adenocarcinoma

Lambros Kordelas, Esther Schwich, Robin Dittrich, Peter A. Horn, Dietrich W. Beelen, Shan He, Ziming Li, Yongfeng Yu, Qingyu Zeng, Yirui Cheng, Wenxiang Ji, Weiliang Xia, Shun Lu

Experimental Cell Research

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesLung CancerSize MeasurementTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer metastasiscarcinogenesisexosomal miRNAexosomeslung cancermicroRNAmiR499amiRNAmTOR pathwaytumor derived exosomes

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Exosomes derived from human umbilical cord mesenchymal stromal cells deliver exogenous miR-145-5p to inhibit pancreatic ductal adenocarcinoma progression

Yixuan Ding, Feng Cao, Haichen Sun, Yecheng Wang, Shuang Liu, Yanchuan Wu. Qingye Cui, Wen Tong Mei, Fei Li

Cancer Letters

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesPancreatic CancerSize MeasurementTechnical NanoparticlesVesicles

145-Exodeliverydrug deliveryexosomeshUCMSChuman umbilical cord mesenchymal stromal cellmicroRNAmiR-145miR-145-5pmiRNAmiRNA transferpancreatic ductal adenocarcinomaPDACtumor treatmentxenograft tumors

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Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway

Shihua Wang, Xiaodong Su, Meiqian Xu, Xian Xiao, Xiaoxia Li, Hongling Li, Armand Keating, and Robert Chunhua Zhao

Stem Cell Research & Therapy

2019

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

AdipocyteAdipocyte ExosomesBreast Cancercell-cell communicationexosomeshippo signaling pathwaymesenchymal stromal/stem celltumor development

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Expression of Glypican 3 Is an Independent Prognostic Biomarker in Primary Gastro-Esophageal Adenocarcinoma and Corresponding Serum Exosomes

Mohammad Rahbari, Mathieu Pecqueux, Daniela Aust, Holger Stephan, Oliver Tiebel, Antonios Chatzigeorgiou, Torsten Tonn, Franziska Baenke et al.

Journal of Clinical Medicine

2019

BiomarkersCancerExosomesExtracellular VesiclesGastro-Esophageal AdenocarcinomaVesicles

diagnostic biomarkereGPC3Glypican 3GPC3

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Extracellular vesicle‑delivered miR‑505‑5p, as a diagnostic biomarker of early lung adenocarcinoma, inhibits cell apoptosis by targeting TP53AIP1

Hua Fang, Yutao Liu, Yaohong He, Yang Jiang, Yaping Wei, Han Liu, Yueqing Gong, Guangyu An

International Journal of Oncology

2019

ApplicationsBiomarkersCancerConcentration MeasurementExtracellular VesiclesLung AdenocarcinomaSize MeasurementTechnical NanoparticlesVesicles

EVsextracellular vesiclesLA biomarkerslung adenocarcinomalung adenocarcinoma biomarkerslung cancerlung cancer biomarkersmiR-382miR-486miR-505miRNAoncogenetargeted deliverytargeted EVs

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Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibit Endometrial Cancer Cell Proliferation and Migration through Delivery of Exogenous miR-302a

Xin Li, Li li Liu, Ju lei Yao, Kai Wang and Hao Ai

Stem Cells International

2019

ApplicationsCancerConcentration MeasurementEndometrial CancerExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Anticancer Therapyendometrial cancerendometrial cancer therapyengineered extracellular vesiclesEV engineeringhUCMSChuman umbilical cord mesenchymalstem cellsmicroRNAmiR-302amiRNAstem cellstumor suppressor miRNAtumor-targeting drug delivery

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Matrix stiffness regulates microvesicle-induced fibroblast activation

Schwager SC, Bordeleau F, Zhang J, Antonyak MA, Cerione RA, Reinhart-King C.

American Journal of Physiology. Cell Physiology

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesiclesZeta Potential

cancer therapycancer treatmentcell contractilityextracellular matrixextracellular secreted vesicleextracellular vesiclesmechanotransductiontraction force

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Regulation of exosomes secretion by low-intensity pulsed ultrasound in lung cancer cells

Qingyu Zeng, Shibin Hong, Xue Wang, Yirui Cheng, Junfeng Sun, Weiliang Xia

Experimental Cell Research

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesLung CancerSize MeasurementTechnical NanoparticlesVesicles

exosome-related diseasesexosomesLIPUSLIPUS/exosome interactionLow-intensity pulsed ultrasoundmTOR

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Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2.

Lu Chen, Le Chen, Zhiyuan Qin, Jinxiu Lei, Sheng Ye, Kui Zeng Hua Wang, Meidan Ying, Jianqing Gao, Su Zeng, Lushan Yu

Acta Pharmaceutica Sinica B

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesRenal Cell CarcinomaSize MeasurementTechnical NanoparticlesVesicles

epigenetic regulationmicroRANmiR-489miR-630miRNAOCT2OCT2 expressiononcotherapyoxaliplatinoxaliplatin resistanceRCCRCC treatmentrenal cancer treatmentrenal cell carcinoma

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Application of polymersomes engineered to target p32 protein for detection of small breast tumors in mice

L Simón-Gracia, P Scodeller, SS Fuentes, V Gómez et al.

Oncotarget

2018

ApplicationsBreast CancerCancerConcentration MeasurementPolymersomesVesicles

LinTT1p32PETpolyethylene glycol-polycaprolactonepolymersomesprecision-guided tumor imagingtriple-negative breast cancertumortumor-associated macrophagestumor-penetrating peptide

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Circular RNA expression in extracellular vesicles isolated from serum of patients with endometrial cancer

Hanzi Xu, Zhen Gong, Yang Shen, Yichen Fang& Shanliang Zhong .

Epigenomics

2018

ApplicationsCancerConcentration MeasurementEndometrial CancerExosomesExtracellular VesiclesSize MeasurementVesicles

Circular RNAsdifferential circRNA expressionendometrial cancerexosomesextracellular vesiclesmiRNAstage III adenocarcinoma

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Communication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis.

C. Probert, T. Dottorini, A. Speakman, S. Hunt, T. Nafee, A. Fazeli, S. Wood, J. E. Brown & V. James

Oncogene

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesProstate CancerSize MeasurementTechnical NanoparticlesVesicles

cancer preventioncancer treatmentcell-cell communicationEV cargoEVsextracellular vesiclesPCaprostate cancerprostate cancer treatmenttargeted EVstumor derived exosomes

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ExoAPP: Exosome-Oriented, Aptamer Nanoprobe-Enabled Surface Proteins Profiling and Detection

Dan Jin, Fan Yang, Yulin Zhang, Li Liu, Yujuan Zhou, Fubing Wang, and Guo-Jun Zhang

Analytical Chemistry

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

cancer diagnosisExoAppexosome-oriented aptamer nanoprobeexosomestargeted EVstumor derived exosomes

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Extracellular Vesicle-Associated mir-21 and mir-144 Are Markedly Elevated in Serum of Patients With Hepatocellular Carcinoma.

Pu C, Huang H, Wang Z, Zou W, Lv Y, Zhou Z, Zhang Q, Qiao L, Wu F and Shao S

Frontiers in Physiology

2018

ApplicationsCancerConcentration MeasurementHepatocellular CarcinomaInstrument ComparisonSize MeasurementTechnical Nanoparticles

cancer biomarkerscancer diagnosiscancer therapyEVsextracellular vesiclesHCCHCC pathogenesishepatocellular carcinomamicroRNAmiR-144miR-21miR-21-5pmiRNAqRT-PCRsequencing analysisserum derived exosomes

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Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment

Shin La Shu, Yunchen Yang, Cheryl L. Allen, Orla Maguire, Hans Minderman et al.

Scientific Reports

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesMelanomaSize MeasurementTechnical NanoparticlesVesicles

cancer diagnosiscancer metastasiscancer therapyexosomesextracellular acidificationHADFHMEXhuman adult dermal fibroblastshuman melanoma-derived exosomesmetastasis developmentmetastasis promotionmicroRNAmiR-155miR-210miRNAmiRNA cargo

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Probing the role of myofibroblast-derived extracellular vesicles in cancer

Higginbotham, Samuel J; Hunt, Stuart; Lambert, Daniel W

Journal of Extracellular Vesicles

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

CAFcancer associated fibroblastscancer cell-derived EVscancer progressionEV cargoEVsexosome cargoextracellular vesiclesfibroblast derived exosomesmicroRNAmiRNAmyofibroblast-derived exosomesmyofibroblastsNOFnormal oral fibroblastssolid tumortumor biomarkerstumor diagnosistumor prognosis

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Salvianolic acid A inhibits tumor-associated angiogenesis by blocking GRP78 secretion

Yang, Y., Zhang, L., La, X. et al. Jürgen Peters

Naunyn-Schmiedeberg's Archives of Pharmacology

2018

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

AngiogenesisAntiangiogenesisdrug resistanct cancer cellsexosomesglucose-regulated protein 78GRP78interactionSAAsalvianolic acid Asalvianolic acidATCMtraditional chinese medicinetumor developmenttumor-secreted GRP78

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Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface

MKS Tang, PYK Yue, PP Ip, RL Huang, HC Lai et al.

Nature Communications

2018

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesOvarian CancerSize MeasurementVesicles

AsciteBiomarkerE-cadherinexosomesHUVECNFκB signalingovarian cancersE-cadtumor angiogenesisβ-catenin

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The Role of Arrestin Domain-Containing 3 in Regulating Endocytic Recycling and Extracellular Vesicle Sorting of Integrin β4 in Breast Cancer

Young Hwa Soung, Shane Ford, Cecilia Yan and Jun Chung

Cancers

2018

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

ARRDC3Arrestin Domain-containing 3Breast CancerBreast Cancer Therapycancer therapyendocytic recyclingEVsextracellular vesiclesintegrin β4ITG 4TNBCtriple-negative breast cancerubiquitination

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Tissue factor mediates microvesicles shedding from MDA-MB-231 breast cancer cells

AM da R Rondon, VH de Almeida, T Gomes et al.

Biochemical and Biophysical Research Communications

2018

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesMicrovesiclesSize MeasurementVesicles

Breast Cancercofilincytoskeletonextracellular vesiclesfasudilLIMKMDA-MB-231microvesiclesRhoA expressionROCKsilencingTissue factor

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Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy

Huishan Guo, Maneka Chitiprolu, Luc Roncevic, Charlotte Javalet, Fiona J. Hemming, My Tran Trung, Lingrui Meng, Elyse Latreille, Christiano Tanese de Souza, Danielle McCulloch, R. Mitchell Baldwin, Rebecca Auer, Jocelyn Côté, Ryan Charles Russell, Rémy Sadoul, Derrick Gibbings

Developmental Cell

2017

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

AcidificationAtg5Autophagycancerendosomeexosomesextracellular vesiclesLC3multivesicular bodytumorV1V0-ATPase

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Breast-cancer extracellular vesicles induce platelet activation and aggregation by tissue factor-independent and -dependent mechanisms

FG Gomes, V Sandim, VH Almeida, AMR Rondon.

Thrombosis Research

2017

ApplicationsBreast CancerCancerConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

AggregationBreast Cancer Derived EVscancer-associated thrombosisMCF-7 EVsMDA-MB-231 EVsplasma coagulationplatelet activationthrombin generationTissue factor

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Caveolin-1 detected in tumor-derived exosomes induces cancer stem cell phenotypes in castration-resistant prostate cancer

Chun-Jung Lin, Andrew Dang, Elizabeth Hernandez, Jer-Tsong Hsieh

Cancer Research

2017

ApplicationsCancerConcentration MeasurementInstrument ComparisonProstate CancerSize MeasurementTechnical Nanoparticles

cancer treatmentcastration-resistant prostate cancerchemoresistanceCRPCCRPC treatment resistancePCaprognostic biomarkerprostate cancerprostate cancer treatmenttargeted deliverytargeted EVstargeted exosomesTDEtherapeutic targettumor derived exosomes

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Larger size extracellular vesicle as early biomarker in patients with metastatic pancreatic cancer

Dong Uk Kim, Francis A San Lucas, Matthew Cagley, Bret Stephens, Feven C Mulu, Jonathan Castillo, Vincent Bernard, Gauri R. Varadhachary, Matthew H. G. Katz, Hector A Alvarez, Anirban Maitra;

Journal of Clinical Oncology

2017

ApplicationsCancerConcentration MeasurementExtracellular VesiclesPancreatic CancerSize MeasurementVesicles

Bioactive MoleculesBiomarkerLiquid biopsymetastatispancreatic cancerPDACpredictorstumor progression

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Mining Extracellular Vesicles for Clinically Relevant Noninvasive Diagnostic Biomarkers in Cancer.

Muhammad Nawaz, Farah Fatima and Jeremy A. Squire.

Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases

2017

BiomarkersCancerExtracellular VesiclesVesicles

Analytical TechnologiesEV isolationexosomesexRNAextracellular vesiclesgenetic profilingLiquid biopsymetastasismiRNAnoninvasive diagnosis

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Pediatric brain tumor cells release exosomes with a miRNA repertoire that differs from exosomes secreted by normal cells

Ágota Tűzesi, Teresia Kling, Anna Wenger, Taral R. Lunavat, Su Chul Jang, Bertil Rydenhag, Jan Lötvall, Steven M. Pollard, Anna Danielsson, Helena Carén.

Oncotarget

2017

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

Braincancer stem cellsexosomesgene expressiongliomaGlioma stem cellmicroRNAmRNA expressionneural stem cellpediatric

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In vivo identification of an HLA?G complex as ubiquitinated protein circulating in exosomes

Estibaliz Alegre, Vera Rebmann, Joel Lemaoult, Carmen Rodriguez, Peter A Horn, Angel Díaz-Lagares, José I Echeveste, Alvaro González

European Journal of Immunology

2013

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD63circulating HLA-G complexesexosomeshuman leukocyte antigen-G (HLA-G)markermicrovesiclesNK cellstumor spreadingUbiquitin

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