ZetaView® Subpopulations Size Fluorescence Zeta Potential Concentration Colocalization Next Generation NTA
Applications
EXTRACELLULAR VESICLES
Research on Exacellular Vesicles is thriving. Nanoparticle Tracking Analysis plays an important role in this development due to in vitro measurement of multiple physical parameters such as size, concentration, surface charge, and phenotype characteristics
Viruses
Nanoparticle Tracking Analysis can be used to quantify total concentration of virions, analyse the amount of successfully loaded virions as well as virus aggregatiion.
Biological nanoparticles, such as extracellular vesicles (EVs), exosomes, lipids, viruses or proteins can be found in almost all fluids of living tissue. The Particle Metrix ZetaView® Nanoparticle Tracking Analysis technology is capable to characterize them reliably in water or physiological buffers. You can simultaneously get information about particle size, particle concentration and surface charge with just one single measurement of a particle sample. Similarly, cluster analysis based on similar properties is possible.
For more information on the ZetaView® or to discuss your requirements, please contact us.
Upcoming Events
GEIVEX 2024
23 October 2024 – 25 October 2024
Palma de Mallorca, Spain
JSEV 2024
28 October 2024 – 29 October 2024
Tokyo, Japan
Get the news
Use of Fluorescence Nanoparticle Tracking Analysis as a tool for quality assessment of EVs
Correct and standardized storage conditions of extracellular vesicles (EVs) are essential prerequisites for the stability of clinical samples and the production of consistent EV batches for therapeutic use.
The loss of EV concentration due to improper storage conditions is associated with a reduced activity and physical integrity.
Check out our new app note on the importance of EV storage conditions and how fluorescence nanoparticle tracking analysis can be used as a quality assessment tool.
Detection of nucleic acid cargo in EVs by using Fluorescence Nanoparticle Tracking Analysis
The use of fluorescence nanoparticle tracking analysis (F-NTA) enables the detection of membrane-associated nucleic acids from EVs.
Analysis of 25 nm functionalized QDs using fluorescence-NTA with ZetaView® QUATT system
Application Note Download Abstract While it is uncertain how far the NTA community is able to push the limits of current technology in order to