Tag: CD63

Your search for CD63 returned 2 articles and 25 publications

Articles

graphic on storage conditions of extracellular vesicles (EVs)
Applications

Use of Fluorescence Nanoparticle Tracking Analysis as a tool for quality assessment of EVs

Correct and standardized storage conditions of extracellular vesicles (EVs) are essential prerequisites for the stability of clinical samples and the production of consistent EV batches for therapeutic use.
The loss of EV concentration due to improper storage conditions is associated with a reduced activity and physical integrity.
Check out our new app note on the importance of EV storage conditions and how fluorescence nanoparticle tracking analysis can be used as a quality assessment tool.

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27. June 2024

Publications

MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells.

Albanese M, Chen Y-FA, Hüls C, Gärtner K, Tagawa T, Mejias-Perez E, et al.

PLOS GENETICS

2021

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

cargoCD63cell-cell communicationdonor cellexosomesextracellular vesiclesmiRNAPKH26 membrane dyetarget cellsviral miRNAs

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Tumour-derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8-mediated creatine import in NPM1-mutated acute myeloid leukaemia

Meixi Peng, Jun Ren, Yipei Jing, Xueke Jiang, Qiaoling Xiao, Junpeng Huang, Yonghong Tao, Li Lei, Xin Wang, Zailin Yang, Zesong Yang, Qian Zhan, Can Lin, Guoxiang Jin, Xian Zhang, Ling Zhang

Journal of Extracellular Vesicles

2021

ApplicationsBreast CancerCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD63paclitaxeltetraspanintriple-negative breast cancervinorelbine

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A dual signal amplification method for exosome detection based on DNA dendrimer self-assembly.

Meiling Gao, Fang He, Bin-Cheng Yin and Bang-Ce Ye

Analyst

2019

ApplicationsCancerConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

cancer biomarkerscancer diagnosiscancer metastasiscancer prognosiscancer therapycancer treatmentCD63CD63 aptamerdendrimerexosome detectionmagnetic beadstumor biomarkerstumor derived exosomestumor development

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Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material

André Görgens, Michel Bremer, Rita Ferrer-Tur, Florian Murke, Tobias Tertel, Peter A. Horn, Sebastian Thalmann, Joshua A. Welsh, Christine Probst, Coralié Guerin, Chantal M. Boulanger, Jennifer C. Jones, Helmut Hanenberg, Uta Erdbrügger, Joanne Lannigan, Franz L. Ricklefs, Samir El-Andaloussi and Bernd Giebel

Journal of Extracellular Vesicles

2019

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementSmall Extracellular VesiclesTechnical NanoparticlesVesicles

Antibody LabellingCD63ev characterizationflow cytometrysEVssingle EV detectionsmall EV characterizationsmall EV identificationsmall EVssubpopulations

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Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy

X Gao, N Ran, X Dong, B Zuo, R Yang, Q Zhou et al.

Science Translational Medicine

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

cargoCD63CP05dystrophin expressionexosomal anchor peptideexosome captureexosome engineeringexosome modificationmuscular dystrophypeptidesplicing

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Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells

C DeMarino, ML Pleet, M Cowen, RA Barclay et al.

Scientific Reports

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesViruses

cART-altered EV contentCD63CD81CD9DemeclocyclineDoxycyclineextracellular vesiclesFDA-approved drugsHIV-1MethacyclineMinocyclinenon-coding viral RNAOxycyclineOxytetracyclineSCRT pathwayTAR RNtetracyclineVPS4

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Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes

Lakhter A, Pratt RE, Moore RE, Doucette KK1, Maier BF, DiMeglio LA, Sims EK

Diabetologia

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

Beta Cell Signal TransductioncalreticulincaspaseCD63CD9cell linescytokinediabetes biomarkerdiabetes predictiondiabetes preventionEVsexomiRexomiR-21extracellular vesicleshumanmicroRNAmiR-21miRNAtype 1 diabetes

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Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins

Nasibeh Karimi, Aleksander Cvjetkovic, Su Chul Jang, Rossella Crescitelli, Mohammad Ali Hosseinpour Feizi, Rienk Nieuwland, Jan Lötvall, Cecilia Lässer.

Cellular and Molecular Life Sciences

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Apo-A1CD63CD81CD9Density cushionexosomesextracellular vesiclesFlotillin-1LipoproteinsMass spectrometryPlasmaproteomicsSerumSize-exclusion chromatography

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Exosomal microRNAs derived from human amniotic epithelial cells accelerate wound healing by promoting the proliferation and migration of fibroblasts

Bin Zhao, Xiaodong Li, Xiaomin Shi, Xueqin Shi, Wei Zhang, Gaofeng Wu, Xujie Wang, Linlin Su, and Dahai Hu.

Stem Cells International

2018

ApplicationsConcentration MeasurementInstrument ComparisonSize MeasurementTechnical NanoparticlesZeta Potential

Accelerated Wound HealingCD63CD81CD9cell-cell communicationexosomal markersexosomal miRNAhAECshAECs-derived exosomeshuman amniotic epithelial cells-derived exosomesmicroRNAmiRNAmiRNA cargoprotein cargowound healing

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Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy

S Chettimada, DR Lorenz, V Misra, ST Dillon et al.

Scientific Reports

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesViruses

CD63CD81CD9CRPD14exosome cargoHIVHLA-AHLA-Bimmunological markersimmunomodulationoxidative stressplasma exosome

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Exosomes from Suxiao Jiuxin Pill-treated cardiac mesenchymal stem cells decrease H3K27 demethylase UTX expression in mouse cardiomyocytes in vitro

Xiao-fen Ruan, Yong-jun Li, Cheng-wei Ju, Yan Shen, Wei Lei, Can Chen, Yang Li, Hong Yu, Yu-tao Liu, Il-man Kim, Xiao-long Wang, Neal L Weintraub & Yao-liang Tang.

Acta Pharmacologica Sinica

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Borneolcardiac mesenchymal stem cellsCD63CD81epigenetic regulationexosomesH3K27 demethylasesH3K27 methylasesPCNASuxiao Jiuxin pilltetramethylpyrazinetraditional chinese medicineUTX

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Exosomes originating from MSCs stimulated with TGF-β and IFN-γ promote Treg differentiation

Zhang, Q., Fu, L., Liang, Y., Guo, Z., Wang, L., Ma, C. and Wang, H.

Journal of Cellular Physiology

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD63CD81CD9cytokinesexosomesIDOIFN-γIL-10immune modulationimmunosuppressive activitymesenchymal stem cellsMSC-exTGF-βtherapeutic effectumbilical cord-derived MSCs

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Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modify Microglial Response and Improve Clinical Outcomes in Experimental Spinal Cord Injury

Katherine A. Ruppert, Tin T. Nguyen, Karthik S. Prabhakara, Naama E. Toledano Furman, Amit K. Srivastava, Matthew T. Harting, Charles S. Cox Jr. & Scott D. Olson.

Scientific Reports - Nature

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD107CD63CD81CD9COX2/PGE2 pathwaycytokinesextracellular vesiclesinflammation attenuationinflammatory effectslocomotor recoverymesenchymal stromal cellsMicroglial ResponseSpinal Cord Injury

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Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

Ryan P. McNamara, Lindsey M. Costantini, T. Alix Myers, Blake Schouest, Nicholas J. Maness, Jack D. Griffith, Blossom A. Damania, Andrew G. MacLean, Dirk P. Dittmer.

mBio

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesiclesViruses

AIDSCD4CD63CD81exosomesextracellular vesiclesFlotillinHIVlentivirusesmicrovesiclesNefSIV

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Placental exosome-mediated Bta-miR-499-Lin28B/let-7 axis regulates inflammatory bias during early pregnancy

G Zhao, C Yang, J Yang, P Liu, K Jiang, A Shaukat et al.

Cell Death & Disease

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Abnormal Inflammatory BiasBta-miR-499CD63CD9exosomesLin28B/let-7 axismiRNANF-κBplacentapregnancy

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Suxiao Jiuxin pill promotes exosome secretion from mouse cardiac mesenchymal stem cells in vitro

Xiao-fen Ruan, Cheng-wei Ju, Yan Shen, Yu-tao Liu, Il-man Kim, Hong Yu, Neal Weintraub, Xiao-long Wang & Yao-liang Tang.

Acta Pharmacologica Sinica

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Acute Myocardial IschemiaBorneolcardiac mesenchymal stem cellsCD63exosomesGTPasenSMase2Rab27Suxiao Jiuxin pilltetramethylpyrazinetraditional chinese medicineTsg101

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The Serum Exosome Derived MicroRNA-135a, -193b, and-384 Were Potential Alzheimer’s Disease Biomarkers

YANG Ting Ting, LIU Chen Geng, GAO Shi Chao, ZHANG Yi, WANG Pei Chang.

Biomedical and Environmental Sciences

2018

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

Alzheimer’s DiseaseAPP/PS1 Transgenic MiceBACE-1BiomarkerCD63CD9differential expressionexosomal miRNAexosomehippocampusmicroRNAmiR-135amiR-193bmiR-384

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Urinary Exosomes and Exosomal CCL2 mRNA as Biomarkers of Active Histologic Injury in IgA Nephropathy

Ye Feng, Lin-Li Lv, Wei-Jun Wu, Zuo-Lin Li, JunChen, Hai-Feng Ni et al.

The American Journal of Pathology

2018

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementTechnical NanoparticlesVesicles

AlixAquaproin 2CD63exosome markersexosomesIgA nephropathyIgANIgAN diagnosisnephrinnon-invasive biomarkersrenal cell markersrenal disease diagnosisrenal injuryrenal pathologyurinary exosomes

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A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents

Inas Helwa, Jingwen Cai, Michelle D. Drewry, Arthur Zimmerman, Michael B. Dinkins, Mariam Lotfy Khaled, Mutsa Seremwe, W. Michael Dismuke, Erhard Bieberich, W. Daniel Stamer, Mark W. Hamrick, Yutao Liu

PLOS ONE

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesiclesZeta Potential

CD63CD9differential ultracentrifugationexosomal RNAhigh-density lipoproteinshsa-miR-16hsa-miR-451human serumpolyethylene glycolTEM

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Exosome production and its regulation of EGFR during wound healing in renal tubular cells

Zhou X, Zhang W, Yao Q, Zhang H, Dong G, Zhang M, Liu Y, Chen JK, Dong Z.

American journal of physiology. Renal physiology

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

CD63EGFRexosomesGW4869kidneymanumycin ATEMtransfer of genetic information between cellsTsg101wound healing

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Extracellular vesicles from KSHV-infected endothelial cells activate the complement system

JL Kang, J Park, SJ Gao, MS Lee.

Oncotarget

2017

ApplicationsConcentration MeasurementExtracellular VesiclesMicroparticlesSize MeasurementTechnical NanoparticlesVesiclesViruses

Alternative Complement PathwayCD63CD81complement systemendothelial cellsextracellular vesiclesherpesvirusHSP70innate immunityKSHVNF-κB pathwayproteomics analysis

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Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents

Verena Börger, Michel Bremer, Rita Ferrer-Tur, Lena Gockeln, Oumaima Stambouli, Amina Becic and Bernd Giebel

International Journal of Molecular Sciences

2017

ApplicationsConcentration MeasurementExtracellular VesiclesSize MeasurementVesicles

AlixAngiogenesisAnti-inflammatory CapabilitiesApoptosisCD63CD81CD9cell proliferationcell therapycytokinesexosomesextracellular vesiclesfibrosisimmunomodulationmesenchymal stem/stromal cellsmicrovesiclesneurogenesisoxidative stressTsg101

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Novel Therapy for Glioblastoma Multiforme by Restoring LRRC4 in Tumor Cells: LRRC4 Inhibits Tumor-Infitrating Regulatory T Cells by Cytokine and Programmed Cell Death 1-Containing Exosomes

Peiyao Li, Jianbo Feng, Yang Liu, Qiang Liu, Li Fan, Qing Liu, Xiaoling She, Changhong Liu, Tao Liu, Chunhua Zhao, Wei Wang, Guiyuan Li and Minghua Wu.

Frontiers in Immunology

2017

ApplicationsConcentration MeasurementExosomesExtracellular VesiclesSize Measurement

CCR4CD63CD81CD9exosomeGBM immune microenvironmentGlioblastomaHSP70LRRC4methylation-mediated LRRC4 inactivationmiRNA expressionprogrammed cell death 1regulatory T cellstumor-infiltrating lymphocytes

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Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium

Wang Y, Zhang L, Li Y, Chen L, Wang X, Guo W, Zhang X, Qin G, He S, Zimmerman A, Liu Y, Kim I, Weintraub NL, Tang Y.

International Journal of Cardiology

2015

ApplicationsConcentration MeasurementSize MeasurementZeta Potential

ApoptosiscardiomyocytesCD63exosomesinduced pluripotent stem cellsmicroRNAmicrovesiclesmouse cardiac fibroblast (CF)-derived iPS cellsoxidative stressTsg101

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In vivo identification of an HLA?G complex as ubiquitinated protein circulating in exosomes

Estibaliz Alegre, Vera Rebmann, Joel Lemaoult, Carmen Rodriguez, Peter A Horn, Angel Díaz-Lagares, José I Echeveste, Alvaro González

European Journal of Immunology

2013

ApplicationsCancerConcentration MeasurementExosomesExtracellular VesiclesSize MeasurementVesicles

CD63circulating HLA-G complexesexosomeshuman leukocyte antigen-G (HLA-G)markermicrovesiclesNK cellstumor spreadingUbiquitin

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