Particle Metrix Exosomes Company History Tech Note App Note NTA See what you measure
The preparation of high-value biological material, such as proteins, requires a multi-step procedure of separation and purification. Each step must be optimized to reach full efficiency of yield.
Reliability of concentration measurements with the Particle Metrix ZetaView® Nanoparticle Tracking Analyzer
Concentration levels of extracellular vesicles have a high clinical potential as a reference for disease.
Nanoparticle Tracking Analysis of fluorescent labelled bionanoparticles, such as vesicles or liposomes, is an efficient technique for quantification of size and total concentration.
Shown with four-fold labeled EVs: Multi-wavelength NTA reduces total measurement time, minimizes the amount of sample required, and improves experimental reproducibility.
The particular area of expertise focuses on investigating the roles of extracellular vesicles (EVs) in cancer and cellular stress responses.
Nanoparticle Tracking Analysis (NTA) combined with surface charge measurement enables the user to gain bio-chemical information about particle surface.
Traditionally, detection of fluorescent particles (F-NTA) has been shown to be challenging due to bleaching effects known from laser induced fluorescence techniques (LIF).
Full recovery of samples measured by a nanoparticle tracking analyzer (NTA) often becomes challenging particularly if the samples are intended for further use after measurement.
From the same sample you get the parameters: number concentration, size, electrophoresis surface charge, sub-populations and fluorescence phenotyping in little time.
Identification of Exosomes using the tetraspanins CD9, CD63, CD81 and Particle Metrix ZetaView® fluorescent Nanoparticle Tracking (F-NTA)
Nanoparticle Tracking Analysis (NTA) has emerged as the state-of the-art method for size and concentration characterization of exosomes and extracellular vesicles.
Here we report a unique technology for rapid determination of membranous particles along with an analysis of multiple EV biomarkers. In spite of the experimental sophistication, the operational costs of our instrument are kept to a minimum.
Purity check of Extracellular Vesicle preparations by Particle Metrix ZetaView® Nanoparticle Tracking Analysis
Over the past decade Nanoparticle Tracking Analysis (NTA) has emerged as an essential characterization tool for Extracellular Vesicle and Exosome research.
Identification of DNA / RNA containing Extracellular Vesicles with DAPI and Particle Metrix ZetaView® Nanoparticle Tracking
Here we report an easy and quick method to analyse size and concentration of nucleic acid containing EVs by fluorescent NTA (f-NTA) after staining with DAPI.
Identification of platelet-derived Exosomes in plasma samples with Particle Metrix ZetaView® Nanoparticle Tracking
Here we report a unique method to identify platelet-derived Exosomes from plasma samples using specific fluorescently labelled CD41 antibody and the Particle Metrix ZetaView® instrument.
Classic NTA instruments are equipped with one laser, requiring phenotyping in sequence. Multi-fluorescence detection of four biomarkers on one sample by NTA is shown for the very first time.
DKSH and Particle Metrix have signed a distribution agreement to provide sales and technical services for its ZetaView® nanoparticle tracking analysis (NTA) system in the Japanese life science market.
DKSH, the leading Market Expansion Services provider with focus on Asia, and Particle Metrix, a manufacturer of particle analysis instruments headquartered in Germany, have signed the first exclusive agreement in Australia and China.
To anticipate the answer: With the ZetaView®.
Particle Metrix now introduces two additional types of NTA Cell Assemblies: The new types are designed for concentration, size and fluorescence detection. When working in (bio-) safety level environment, X-NTA ensures secure handling for potentially contaminating samples. In addition, zeta potential option is featured with Z-NTA Cell Assemblies.
Cell Guidance Systems use the ZetaView® from Particle Metrix for exosome research and quality control
Particle Metrix reports on how Cell Guidance Systems use the ZetaView® particle characterization system for exosome research and quality control.
The Institute for Transfusion Medicine at the University Hospital of Duisburg-Essen in Germany uses the ZetaView® from Particle Metrix to quantify extracellular vesicles
Particle Metrix reports on the work of the Giebel Working Group on the Developmental Biology of Stem Cells in the Institute for Transfusion Medicine at the University Hospital of Duisburg-Essen
The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes
Particle Metrix reports on the work of the Baur Laboratory in the Department of Dermatology at the University Hospital of Erlangen.
The Ottawa Hospital Research Institute uses the ZetaView® from Particle Metrix to study membrane microparticles as potential biomarkers for underlying diseases
Particle Metrix reports on the work of the Burger Laboratory at Ottawa Hospital Research Institute.
Augusta University’s Department of Cellular Biology & Anatomy is studying exosomes using ZetaView® from Particle Metrix to aid in identification of potential biomarkers
Particle Metrix reports on the work in the Liu Laboratory at Augusta University which is studying exosomes where size and concentration are critical parameters.