ZetaView® Subpopulations Size Fluorescence Zeta Potential Concentration Colocalization Next Generation NTA

Applications

3d render of cells secreting exosomes

EXTRACELLULAR VESICLES

Research on Exacellular Vesicles is thriving. Nanoparticle Tracking Analysis plays an important role in this development due to in vitro measurement of multiple physical parameters such as size, concentration, surface charge, and phenotype characteristics

particlemetrix-virus

Viruses

Nanoparticle Tracking Analysis can be used to quantify total concentration of virions, analyse the amount of successfully loaded virions as well as virus aggregatiion.

Biological nanoparticles, such as extracellular vesicles (EVs), exosomes, lipids, viruses or proteins can be found in almost all fluids of living tissue. The Particle Metrix ZetaView® Nanoparticle Tracking Analysis technology is capable to characterize them reliably in water or physiological buffers. You can simultaneously get information about particle size, particle concentration and surface charge with just one single measurement of a particle sample. Similarly, cluster analysis based on similar properties is possible.

The x30 Series at a Glance

For more information on the ZetaView® or to discuss your requirements, please contact us.

Upcoming Events

SelectBIO – Next-Gen Flow Cytometry & EV Instrumentation 2024

2 December 2024 – 3 December 2024
Oregon City/ Portland, United States

CSEVP 2024

2 December 2024 – 4 December 2024
Rome, Italy

UKEV Forum 2024

16 December 2024 – 18 December 2024
Newcastle, United Kingdom

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graphic on storage conditions of extracellular vesicles (EVs)
Applications

Use of Fluorescence Nanoparticle Tracking Analysis as a tool for quality assessment of EVs

Correct and standardized storage conditions of extracellular vesicles (EVs) are essential prerequisites for the stability of clinical samples and the production of consistent EV batches for therapeutic use.
The loss of EV concentration due to improper storage conditions is associated with a reduced activity and physical integrity.
Check out our new app note on the importance of EV storage conditions and how fluorescence nanoparticle tracking analysis can be used as a quality assessment tool.

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