made to explore the colorful nanocosmos
ZetaView® Evolution
Explore the colorful nanocosmos with the new ZetaView® Evolution.
Engineered for precision, it combines Size, Concentration, Zeta Potential and multi-channel fluorescence analysis in one powerful system.
Sets new standards in Nanoparticle Analysis- with cutting-edge colocalization capabilities and unmatched sensitivity.
ZetaView® Evolution - Nanoparticle Tracking Analyzer
Our ZetaView® Evolution Nanoparticle Tracking Analyzer defines a new standard in nanoparticle characterization. It features calibration-free Size and Concentration measurements, cutting-edge Concentration Scanning Technology, direct Zeta Potential analysis across up to 11 highly sensitive Fluorescence channels by the use of up to four different excitation lasers. Thereby our ZetaView® Evolution enables precise and detailed full sample characterization across a wide range of applications. The integrated Colocalization NTA (C-NTA) allows for simultaneous detection of biomarkers on individual particles - ideal for Extracellular Vesicle (EV) research, Virus characterization and targeted drug delivery studies.
Discover the full power of multiparameter nanoparticle analysis with ZetaView® Evolution - engineered for high-performance analysis, proudly Made in Germany.
- Scanning NTA for size determination via Brownian motion tracking
- Calibration free size & concentration determination
- Concentration Scanning Technology - Concentration range: 10^5 – 10^9 particles/ml
- Zeta Potential measurement - Zeta potential working range: -500mV - +500mV
- Sensitivity improved Fluorescence NTA (F-NTA) with up to 4 lasers and 11 fluorecence channels
- Colocalization NTA (C-NTA): Colocalization of two fluorophores on one particle
- Size range: 10 – 1000nm (sample and laser dependent)
- Fluorescence sensitivity level: < 20AF488 molecules
- Available lasers: 405nm, 488nm, 520nm, 640nm, 660nm
- pH range: 1 - 13
Nanoparticle Tracking Analysis
Nanoparticle Tracking Analysis (NTA) is a widely used technique to characterize nanoparticles in liquids. It combines laser light scattering and video microscopy to visualize and track the Brownian motion of individual particles. By analyzing their movement, the particle size (hydrodynamic diameter) and concentration can be determined using the Stokes-Einstein equation.
New Concentration Scanning Technology
Our new innovative Concentration Scanning Technology revolutionizes nanoparticle concentration measurements. The advanced
technology captures all particles by scanning the entire measurement volume. This enables:
- Calibration free measurements
- Direct comparability between different sample types
- Direct comparability between fluorescence and scatter channels
- Precise, reproducible results across a wide concentration range: 10^5 – 10^9 particles/ml
Zeta Potential
Zeta Potential is the electrical potential at the slipping plane of a particle suspended in a fluid. It indicates the degree of electrostatic repulsion or
attraction between particles and is a key parameter for predicting the stability of colloidal dispersions. A high absolute zeta potential (either positive or negative) suggests strong repulsive forces, which helps prevent particle aggregation. The ZetaView® Evolution can measure Zeta potential directly inside its quartz glass
measurement cell – no need for disposables.
F-NTA: measure up to 11 subpopulations in your sample
By using the fluorescence mode (F-NTA), more specific results can be obtained, since impurities like salt precipitates or protein aggregates do not impact the measurement result. Our ZetaView® Evolution features:
- Up to 4 lasers: 405nm, 488nm, 520nm and 640nm or 660nm
- Up to 11 fluorescence channels with customized filters
- Improved sensitivity level: <20AF488 molecules (<10 binding sites)
ZetaSphere software
By combining the popular and intuitive ZetaView software with the requirements for multi-level sample analysis, we created the new ZetaSphere
software – designed for the perfect user experience.
Highlights:
- Predefined settings for different applications
- Live size and concentration statistics
- Complete multiparameter sample reporting
- Switch between lasers with one click
- Database event logging for data integrity
ZetaView® Evolution – Tailored performance for every research need
The ZetaView® Evolution offers flexible system configurations - mono, twin and quatt - designed to meet the diverse demands of nanoparticle research. Each configuration delivers core capabilities such as size and concentration measurement with optional enhanced features like fluorescence detection and colocalization for deeper sample insights. All optional features and lasers are also available as system upgrades any time.
Whether you're tracking a single parameter or analyzing multiple fluorescent subpopulations, this comparison helps you to identify the ideal Evolution setup for your workflow. From a single-laser entry model to a four-laser, 11-channel powerhouse - ZetaView® Evolution adapts to your science.
| MONO | TWIN | QUATT | |
|---|---|---|---|
| Size | ✓ | ✓ | ✓ |
| Concentration | ✓ | ✓ | ✓ |
| Zeta Potential | optional | optional | optional |
| Fluorescence | optional | ✓ | ✓ |
| Colocalization | x | optional | optional |
| Laser | 1* | 2* | 4 |
| Fluorescence Channels | 1–3 | 2–6 | 4–11 |
Discover the colorful nanocosmos
Discover the benefits of ZetaView® Evolution for your research – contact our team for a personalized consultation or a live demo!
